Mouse Anti-RNH1 Monoclonal Antibody – Cat# MBS6144089

Western Blot analysis of RNH1 expression in transfected 293T cell line by RNH1 monoclonal antibody. ane 1: RNH1 transfected lysate (5kD). Lane 2: Non-transfected lysate.

RNH1 Antibody – Mouse Monoclonal

Name: RNH1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6144089
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6144089

Ribonuclease inhibitor 1 (RNH1) the placental ribonuclease inhibitor, is an acid protein with a molecular weight of 50kD. RNH1 is a member of a family of proteinaceous cytoplasmic RNase inhibitors that are expressed in many tissues and bind to both… More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RNH1, Monoclonal Antibody

Full Product Name

RNH1 (Ribonuclease Inhibitor, Placental Ribonuclease Inhibitor, Placental RNase Inhibitor, Ribonuclease/Angiogenin Inhibitor 1, RAI, PRI, RNH) (Biotin)

Product Gene Name

anti-RNH1 antibody

Clonality

Monoclonal

Isotype

IgG2b,k

Clone Number

3F5

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human RNH1.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Full length recombinant corresponding to human RNH1, aa1-462 (AAH11500) with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS

Conjugate

Biotin

Product Categories/Family for anti-RNH1 antibody

Antibodies; Enzymes; Ribonuclease

Applications Tested/Suitable for anti-RNH1 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-RNH1 antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-RNH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RNH1 purchase

MBS6144089 is an antibody targeting RNH1. Also known as RNH1 (Ribonuclease Inhibitor, Placental Ribonuclease Inhibitor, Placental RNase Inhibitor, Ribonuclease/Angiogenin Inhibitor 1, RAI, PRI, RNH) (Biotin). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for RNH1. It may not necessarily be applicable to this product.

NCBI GI #

15079320

NCBI GeneID

6050

NCBI Accession #

BC011500

NCBI Related Accession #

AAH11500

UniProt Related Accession #

P13489

NCBI Official Full Name

Homo sapiens ribonuclease/angiogenin inhibitor 1, mRNA

NCBI Official Synonym Full Names

ribonuclease/angiogenin inhibitor 1

NCBI Official Symbol

RNH1

NCBI Official Synonym Symbols

RAI; RNH

Protein Family

Probable ribonuclease

NCBI Protein Information

ribonuclease inhibitor

NCBI Summary for RNH1

Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]

Research Articles on RNH1

1. This study first time revealed in vivo role of RNH1. This study report that RNH1 is important for embryonic development and erythropoiesis. RNH1 binds to ribosomes and regulates erythropoiesis by controlling translation of the erythroid transcription factor GATA1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.