• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ADCY2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6145799

ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ADCY2, Monoclonal Antibody
Full Product Name
ADCY2 (Adenylate Cyclase Type 2, Adenylate Cyclase Type II, ATP Pyrophosphate-lyase 2, Adenylyl Cyclase 2, ADCY2, KIAA1060) (FITC)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
1D4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human ADCY2.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
103,158 Da
3D Structure
ModBase 3D Structure for Q08462
Immunogen
Partial recombinant corresponding to aa977-1086 from human ADCY2 (NP_065433) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
GKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNVAS
Conjugate
FITC

Product Categories/Family for anti-ADCY2 antibody

Applications Tested/Suitable for anti-ADCY2 antibody
ELISA (EIA)
Application Notes for anti-ADCY2 antibody
Applications are based on unconjugated antibody.

Testing Data of anti-ADCY2 antibody

Detection limit for recombinant GST tagged ADCY2 is ~1ng/ml as a capture antibody.
Mouse Anti-ADCY2 Monoclonal Antibody – Cat# MBS6145799

Testing Data of anti-ADCY2 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between GNAS and ADCY2. HeLa cells were stained with GNAS rabbit purified polyclonal 1:1200 and ADCY2 mouse monoclonal antibody 1:50. Signals were detected by 30 Detection Kit 613 (red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex.
Mouse Anti-ADCY2 Monoclonal Antibody, Testing Data – Cat# MBS6145799

Other Notes

Small volumes of anti-ADCY2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADCY2 purchase

MBS6145799 is an antibody targeting ADCY2. Also known as ADCY2 (Adenylate Cyclase Type 2, Adenylate Cyclase Type II, ATP Pyrophosphate-lyase 2, Adenylyl Cyclase 2, ADCY2, KIAA1060) (FITC). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ADCY2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
adenylate cyclase type 2
NCBI Official Synonym Full Names
adenylate cyclase 2 (brain)
NCBI Official Symbol
ADCY2
NCBI Official Synonym Symbols
AC2; HBAC2
UniProt Protein Name
Adenylate cyclase type 2
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 2; Adenylate cyclase type II; Adenylyl cyclase 2
Protein Family
UniProt Gene Name
ADCY2
UniProt Synonym Gene Names
KIAA1060
NCBI Protein Information
adenylate cyclase type 2; 3',5'-cyclic AMP synthetase; ATP pyrophosphate-lyase 2; adenylate cyclase II; adenylate cyclase type II; adenylyl cyclase 2; type II adenylate cyclase

UniProt Comments for ADCY2

Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors ().
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ADCY2 antibody

 Reference Product  PubMed Publications
 ADCY1 antibody  >2 publications with ADCY2 and ADCY1
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000