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Adenosine A3 Receptor (ADORA3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS614953

MBS614953 is an antibody targeting ADORA3. Also known as Anti - Adenosine A3 Receptor (A3R). Reactive in Human. Host: RabbitSource: Human. More details

$905 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Adenosine A3 Receptor (ADORA3), Polyclonal Antibody
Full Product Name
Anti - Adenosine A3 Receptor (A3R)
Product Gene Name
Product Synonym Names
Adenosine A3 Receptor (A3R)
Clonality
Polyclonal
Isotype
IgG
Host
Host: Rabbit
Source: Human
Species Reactivity
Human
Form/Format
Serum
Supplied as a liquid, neat serum, 40% glycerol.
Purity/Purification
Serum
Specificity
The human A3R peptide shows only 46% homology (7/15 AA) with rat and 20% (3/15 AA) with sheep A3R sequences. We recommend the use of A3R31 that is made to the rat A3R sequence for the detection of rat A3R. Antibody crossreactivity in various species is not established. Control peptides, because of their low MW (<3kD), are not suitable for Western. It should be used for ELISA or antibody blocking to confirm antibody specificity
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
847 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (112025970..112106597, complement). Location: 1p13.2
3D Structure
ModBase 3D Structure for Q6LD47
Immunogen
A 15 amino acid sequence corresponding to human A3R gene (1). This region corresponds to the 3rd extracellular domain. A cysteine has been added at the NH2 terminus for coupling to KLH.

Product Categories/Family for anti-ADORA3 antibody

Applications Tested/Suitable for anti-ADORA3 antibody
ELISA, Western Blot
Application Notes for anti-ADORA3 antibody
Suitable for use in ELISA, Western Blotting. Other applications not tested.
Dilution: Western Blot: 1:1000-1:5000 for neat serum and 1-10 mg/ml for affinity pure using ECL. Based upon mRNA studies, the A3R has been found in rat testis and lung, kidney, heart and brain (1). Other studies have found the mRNA to be highest in lung, spleen, and pineal glands, and to a moderate levels in brain, kidney, and testis (2). It has been found in lung, liver, kidney, and heart and very little in skeletal muscle and brain (3).
ELISA: 1:10,000-50,000 using 50-100ng control peptide/well.
Optimal dilutions to be determined by the researcher.

Product References and Citations for anti-ADORA3 antibody

• 1. Zhou, Q-Y, et al (1992) Proc. Natl. Acad. Sci. 89, 7432-74361; Tucker, AL and Linden, J (1993) Cardiovascular Res. 27, 62-67; Olah, ME and Stile, G (1995) Ann. Rev. Pharmacol. 35, 581-606;
• 2. Linden J et al (1993) Mol. Pharmacol. 44, 524-532;
• 3. Sajjadi, FG et al (1993) BBA 1179, 105-107

Other Notes

Small volumes of anti-ADORA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADORA3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
adenosine A3 receptor
NCBI Official Synonym Full Names
adenosine A3 receptor
NCBI Official Symbol
ADORA3
NCBI Official Synonym Symbols
A3AR; AD026; bA552M11.5; RP11-552M11.7
UniProt Protein Name
Adenosine A3 receptor protein
Protein Family
UniProt Gene Name
adenosine A3 receptor
UniProt Entry Name
Q6LD47_HUMAN
NCBI Protein Information
adenosine receptor A3; OTTHUMP00000013476; OTTHUMP00000013479; OTTHUMP00000013739; OTTHUMP00000082917

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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