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ARL6IP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS615726

Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA (1). Although apoptosis induced by endoplasmic reticulum… More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ARMER (ARL6IP1), Polyclonal Antibody
Full Product Name
ARMER, CT (ARL6IP, AIP1)
Product Gene Name
anti-ARL6IP1 antibody
Product Synonym Names
Anti -ARMER, CT (ARL6IP, AIP1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Highly Purified
Purified by ion exchange chromatography.
Specificity
Recognizes human ARMER. Species Crossreactivity: Mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
23,363 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (18802991..18812894, complement). Location: 16p12-p11.2
OMIM
607669
3D Structure
ModBase 3D Structure for Q15041
Immunogen
Peptide corresponding to 15 amino acids near the C-terminus of human ARMER (GenBank accession no. Q15041).

Product Categories/Family for anti-ARL6IP1 antibody

Antibodies; Abs to Apoptosis
Applications Tested/Suitable for anti-ARL6IP1 antibody
Western Blot (WB)
Application Notes for anti-ARL6IP1 antibody
Can be used for detection of ARMER by Western blot at 0.5 to 2ug/ml.

Western Blot (WB) of anti-ARL6IP1 antibody

Western blot ana-lysis of ARMER in human bladder cell lysates with anti-ARMER (CT) at (A) 0.5, (B) 1, and (C) 2 ug/ml.
Rabbit Anti-ARL6IP1 Polyclonal Antibody – Cat# MBS615726

Immunohistochemistry (IHC) of anti-ARL6IP1 antibody

Immunohistochemical staining of human bladder tissue using anti-ARMER (CT) at 2ug/ml.
Rabbit Anti-ARL6IP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS615726

Other Notes

Small volumes of anti-ARL6IP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARL6IP1 purchase

MBS615726 is an antibody targeting ARL6IP1. Also known as ARMER, CT (ARL6IP, AIP1). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARL6IP1. It may not necessarily be applicable to this product.

NCBI GI #
24308007
NCBI GeneID
23204
NCBI Accession #
NP_055976.1
UniProt Primary Accession #
Q15041
UniProt Related Accession #
Q15041
GenBank Nucleotide #
NM_015161.1
NCBI Official Full Name
ADP-ribosylation factor-like protein 6-interacting protein 1
NCBI Official Synonym Full Names
ADP-ribosylation factor-like 6 interacting protein 1
NCBI Official Symbol
ARL6IP1
NCBI Official Synonym Symbols
AIP1; ARMER; ARL6IP
UniProt Protein Name
ADP-ribosylation factor-like protein 6-interacting protein 1
Protein Family
ADP-ribosylation factor-like protein 6-interacting protein
UniProt Gene Name
ARL6IP1
UniProt Synonym Gene Names
ARL6IP; KIAA0069; ARL-6-interacting protein 1; Aip-1
UniProt Entry Name
AR6P1_HUMAN
NCBI Protein Information
ADP-ribosylation factor-like protein 6-interacting protein 1; aip-1; ARL-6-interacting protein 1; apoptotic regulator in the membrane of the endoplasmic reticulum

NCBI Summary for ARL6IP1

This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
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UniProt Comments for ARL6IP1

ARL6IP: May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Belongs to the ARL6ip family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p12-p11.2

Cellular Component: membrane; integral to membrane; translocon complex; cytosol

Molecular Function: protein binding

Biological Process: cotranslational protein targeting to membrane

Disease: Spastic Paraplegia 61, Autosomal Recessive
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Research Articles on ARL6IP1

1. Down-regulation of ARL6IP1 expression arrested CaSki cell cycling at the G0/G1 phase and mitigated CaSki cell migration, determined by wound healing assays.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ARL6IP1 antibody

 Reference Product  PubMed Publications
 ARL6 antibody  >1 publications with ARL6IP1 and ARL6

Diseases associated with anti-ARL6IP1 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with ARL6IP1 and Liver Diseases
 Carcinoma Antibodies  >1 publications with ARL6IP1 and Carcinoma
 Carcinoma, Hepatocellular Antibodies  >1 publications with ARL6IP1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with ARL6IP1 and Liver Neoplasms
 Necrosis Antibodies  >1 publications with ARL6IP1 and Necrosis

Organs/Tissues associated with anti-ARL6IP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with ARL6IP1 and Nerve
 Eye Antibodies  >1 publications with ARL6IP1 and Eye
 Embryonic Tissue Antibodies  >1 publications with ARL6IP1 and Embryonic Tissue
 Brain Antibodies  >1 publications with ARL6IP1 and Brain
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