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ZNFN1A3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6161528

MBS6161528 is an antibody targeting ZNFN1A3. Also known as ZNFN1A3 (Zinc Finger Protein Subfamily 1A3, Aiolos, IKAROS Family Zinc Finger 3, IKZF3) (BSA & Azide Free) (PE). Reactive in Human. Host: Mouse. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ZNFN1A3, Monoclonal Antibody
Full Product Name
ZNFN1A3 (Zinc Finger Protein Subfamily 1A3, Aiolos, IKAROS Family Zinc Finger 3, IKZF3) (BSA & Azide Free) (PE)
Product Gene Name
anti-ZNFN1A3 antibody
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
10B2563
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography
Specificity
Recognizes human ZNFN1A.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
606221
3D Structure
ModBase 3D Structure for Q9UKT9
Immunogen
Recombinant protein corresponding to a portion within aa1-510 of human ZNFN1A3. UniProt Accession: Q9UKT9
Conjugate
PE
Hybridoma
Sp2/0 myeloma cells with spleen cells from BALB/c mice.
Special Handling
Light sensitive

Product Categories/Family for anti-ZNFN1A3 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger
Applications Tested/Suitable for anti-ZNFN1A3 antibody
FLISA, Immunofluorescence (IF)
Application Notes for anti-ZNFN1A3 antibody
Applications are based on unconjugated antibody.

Immunofluorescence (IF) of anti-ZNFN1A3 antibody

Immunofluorescence showing ZNFN1A3 in HeLa cells usingMBS606932.
Mouse Anti-ZNFN1A3 Monoclonal Antibody – Cat# MBS6161528

Testing Data of anti-ZNFN1A3 antibody

Detection limit for recombinant GST tagged ZNFN1A3 is ~10ng/ml using MBS606932 as a capture antibody.
Mouse Anti-ZNFN1A3 Monoclonal Antibody, Testing Data – Cat# MBS6161528

Other Notes

Small volumes of anti-ZNFN1A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZNFN1A3. It may not necessarily be applicable to this product.

NCBI GI #
21595809
NCBI Accession #
AAH32707
UniProt Primary Accession #
Q9UKT9
NCBI Official Full Name
IKAROS family zinc finger 3 (Aiolos)
UniProt Protein Name
Zinc finger protein Aiolos
UniProt Synonym Protein Names
Ikaros family zinc finger protein 3
UniProt Gene Name
IKZF3
UniProt Synonym Gene Names
ZNFN1A3
UniProt Entry Name
IKZF3_HUMAN

UniProt Comments for ZNFN1A3

Aiolos: a transcription factor of the ikaros C2H2-type zinc-finger protein family. Plays an important role in the regulation of lymphocyte differentiation. Deletions in Aiolos have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cytoplasm; plasma membrane; nucleus

Molecular Function: protein binding; protein homodimerization activity; protein heterodimerization activity; sequence-specific DNA binding; metal ion binding; transcription factor activity

Biological Process: regulation of apoptosis; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; B cell activation; regulation of lymphocyte differentiation; regulation of B cell differentiation; regulation of B cell proliferation; mesoderm development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZNFN1A3 antibody

 Reference Product  PubMed Publications
 EBF1 antibody  >3 publications with ZNFN1A3 and EBF1
 SHC1 antibody  >2 publications with ZNFN1A3 and SHC1
 IL2RA antibody  >1 publications with ZNFN1A3 and IL2RA
 HRAS antibody  >1 publications with ZNFN1A3 and HRAS

Pathways associated with anti-ZNFN1A3 antibody

 Products by Pathway  Pathway Diagram
 IL2-mediated Signaling Events Pathway antibodies  IL2-mediated Signaling Events Pathway Diagram

Diseases associated with anti-ZNFN1A3 antibody

 Disease Name  Pubmed Publications
 Lymphoma Antibodies  >11 publications with ZNFN1A3 and Lymphoma
 Multiple Myeloma Antibodies  >9 publications with ZNFN1A3 and Multiple Myeloma
 Inflammation Antibodies  >6 publications with ZNFN1A3 and Inflammation
 Asthma Antibodies  >6 publications with ZNFN1A3 and Asthma
 Respiratory Hypersensitivity Antibodies  >4 publications with ZNFN1A3 and Respiratory Hypersensitivity
 Carcinoma Antibodies  >4 publications with ZNFN1A3 and Carcinoma
 Precursor Cell Lymphoblastic Leukemia-Lymphoma Antibodies  >4 publications with ZNFN1A3 and Precursor Cell Lymphoblastic Leukemia-Lymphoma
 Lung Neoplasms Antibodies  >2 publications with ZNFN1A3 and Lung Neoplasms
 Adenocarcinoma Antibodies  >2 publications with ZNFN1A3 and Adenocarcinoma
 Breast Neoplasms Antibodies  >2 publications with ZNFN1A3 and Breast Neoplasms

Organs/Tissues associated with anti-ZNFN1A3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >47 publications with ZNFN1A3 and Blood
 Thymus Antibodies  >6 publications with ZNFN1A3 and Thymus
 Lung Antibodies  >5 publications with ZNFN1A3 and Lung
 Spleen Antibodies  >5 publications with ZNFN1A3 and Spleen
 Eye Antibodies  >1 publications with ZNFN1A3 and Eye
 Lymph Node Antibodies  >1 publications with ZNFN1A3 and Lymph Node
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