Goat Anti-CDHR5 Polyclonal Antibody – Cat# MBS617321

MUCDHL (CDHR5) Antibody – Goat Polyclonal

Name: CDHR5 Antibody; Polyclonal; Goat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS617321
Price: 1090 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS617321

Mucin and cadherin-like protein (MUCDHL), also known as mu-protocadherin, is a 100kD type I transmembrane protein belonging to the protocadherin family of cell adhesion molecules. It is found apically on the brush border of renal proximal tubule epithelial… More details

$1090 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MUCDHL (CDHR5), Polyclonal Antibody

Full Product Name

MUCDHL (Mucin and Cadherin-Like Protein, mu-Protocadherin)

Product Gene Name

anti-CDHR5 antibody

Product Synonym Names

Anti -MUCDHL (Mucin and Cadherin-Like Protein, mu-Protocadherin)

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Mouse

Form/Format

Supplied as a lyophilized powder in PBS with 5% trehalose.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes mouse MUCDHL. In direct ELISAs and Western Blots, this antibody shows approximately 5% crossreactivity with rhMUCDHL.

Preparation and Storage

Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile PBS with 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

69,610 Da

Chromosome Location

chromosome: 11; Location: 11p15.5

3D Structure

ModBase 3D Structure for Q58EZ6

Immunogen

Purified, NS0-derived rmMUCDHL (rmMUCDHL; aa 29 - 479; Accession # NP_082345)

Reconstitution

Reconstitute with sterile PBS. If 0.5ml of PBS is used, the antibody concentration will be 0.2mg/ml.

Product Categories/Family for anti-CDHR5 antibody

Antibodies; Abs to Cadherin

Applications Tested/Suitable for anti-CDHR5 antibody

ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)

Application Notes for anti-CDHR5 antibody

Suitable for use in Western Blot, Flow Cytometry and Direct ELISA.
Dilution: Western Blot: Can be used at 0.1-0.2ug/ml with the appropriate secondary reagents to detect mouse MUCDHL. The detection limit for rmMUCDHL is approximately 1 ng/lane under non-reducing and reducing conditions.
Flow Cytometry: Tested in flow cytometry using primary kidney cells. Dilute this antibody to 25ug/ml and add 10 L of the diluted solution to 1-2.5 x 10e5 cells in a total reaction volume not exceeding 200 L. The binding of unlabeled antibodies may be visualized by adding a secondary developing reagent such as anti-goat IgG conjugated to a fluorochrome.
Direct ELISA: Can be used at 0.5-1.0ug/ml with the appropriate secondary reagents to detect mouse MUCDHL. The detection limit for rmMUCDHL is approximately 0.5 ng/well.

Other Notes

Small volumes of anti-CDHR5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDHR5 purchase

MBS617321 is an antibody targeting CDHR5. Also known as MUCDHL (Mucin and Cadherin-Like Protein, mu-Protocadherin). Reactive in Mouse. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for CDHR5. It may not necessarily be applicable to this product.

NCBI GI #

37181861

NCBI GeneID

53841

UniProt Primary Accession #

Q58EZ6

UniProt Related Accession #

Q58EZ6; Q9HBB8

NCBI Official Full Name

MUCDHL

NCBI Official Synonym Full Names

cadherin-related family member 5

NCBI Official Symbol

CDHR5

NCBI Official Synonym Symbols

MUCDHL; MUPCDH; MU-PCDH; FLJ20219; CDHR5

UniProt Protein Name

Mucin-like protocadherin

Protein Family

Cadherin-related family

UniProt Gene Name

MUPCDH

UniProt Entry Name

Q58EZ6_HUMAN

NCBI Protein Information

cadherin-related family member 5; mu-protocadherin; OTTHUMP00000162884; mucin and cadherin-like protein

NCBI Summary for CDHR5

This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

UniProt Comments for CDHR5

MUCDHL: Acts as a calcium-dependent cell adhesion protein. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: plasma membrane; integral to membrane

Molecular Function: protein binding; beta-catenin binding; calcium ion binding

Biological Process: homophilic cell adhesion; cell adhesion

Research Articles on CDHR5

1. MUCDHL genes are biallelically expressed in multiple fetal and adult tissues both in humans and in mice
2. identifed the human mu-protocadherin ortholog and examined its expression in the developing kidney

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CDHR5 antibody

Disease Name	Pubmed Publications
Cell Transformation, Neoplastic Antibodies	>1 publications with CDHR5 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-CDHR5 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>2 publications with CDHR5 and Kidney
Liver Antibodies	>1 publications with CDHR5 and Liver
Intestine Antibodies	>1 publications with CDHR5 and Intestine