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MCM7 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6187014

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MCM7, Monoclonal Antibody
Full Product Name
MCM7 (Minichromosome Maintenance Complex Component 7, CDABP0042, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS-146) (PE)
Product Gene Name
anti-MCM7 antibody
Product Synonym Names
Minichromosome Maintenance Complex Component 7; CDABP0042; CDC47; MCM2; P1.1-MCM3; P1CDC47; P85MCM; PNAS-146
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1G1
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified
Specificity
Recognizes MCM7.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
42kDa
OMIM
600592
3D Structure
ModBase 3D Structure for P33993
Immunogen
MCM7 (AAH09398, 1aa-389aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSPQNQYPAELMRRFELYFQGPSSSKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQIADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV
Conjugate
PE

Product Categories/Family for anti-MCM7 antibody

Antibodies; DNA Replication; Repair
Applications Tested/Suitable for anti-MCM7 antibody
Western Blot (WB)
Application Notes for anti-MCM7 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-MCM7 antibody

MCM7 monoclonal antibody (M03), clone 1G1. Western Blot analysis of MCM7 expression in Hela S3 NE.
Mouse Anti-MCM7 Monoclonal Antibody – Cat# MBS6187014

Testing Data of anti-MCM7 antibody

Detection limit for recombinant GST tagged MCM7 is 0.1 ng/ml as a capture antibody.
Mouse Anti-MCM7 Monoclonal Antibody, Testing Data – Cat# MBS6187014

Other Notes

Small volumes of anti-MCM7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MCM7 purchase

MBS6187014 is an antibody targeting MCM7. Also known as MCM7 (Minichromosome Maintenance Complex Component 7, CDABP0042, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS-146) (PE). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MCM7. It may not necessarily be applicable to this product.

NCBI GI #
518830597
NCBI GeneID
4176
NCBI Accession #
AAH09398
UniProt Primary Accession #
P33993
UniProt Related Accession #
P33993
GenBank Nucleotide #
NM_005916
NCBI Official Full Name
DNA replication licensing factor MCM7 isoform 2
NCBI Official Synonym Full Names
minichromosome maintenance complex component 7
NCBI Official Symbol
MCM7
NCBI Official Synonym Symbols
MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3
UniProt Protein Name
DNA replication licensing factor MCM7
UniProt Synonym Protein Names
CDC47 homolog; P1.1-MCM3
Protein Family
DNA replication licensing factor
UniProt Gene Name
MCM7
UniProt Synonym Gene Names
CDC47; MCM2
UniProt Entry Name
MCM7_HUMAN
NCBI Protein Information
DNA replication licensing factor MCM7

Research Articles on MCM7

1. Our results indicate that MCM7 may exert certain functions on spindle formation to prevent cytokinesis during early mitosis by regulating CDK1 activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MCM7 antibody

 Reference Product  PubMed Publications
 MCM2 antibody  >100 publications with MCM7 and MCM2
 MCM6 antibody  >53 publications with MCM7 and MCM6
 MCM4 antibody  >47 publications with MCM7 and MCM4
 MCM3 antibody  >40 publications with MCM7 and MCM3
 CDC45 antibody  >33 publications with MCM7 and CDC45
 MCM5 antibody  >32 publications with MCM7 and MCM5
 CDC6 antibody  >31 publications with MCM7 and CDC6
 CDC7 antibody  >9 publications with MCM7 and CDC7
 DBF4 antibody  >6 publications with MCM7 and DBF4

Pathways associated with anti-MCM7 antibody

 Products by Pathway  Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 Assembly Of The Pre-replicative Complex Pathway antibodies  Assembly Of The Pre-replicative Complex Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram

Diseases associated with anti-MCM7 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >109 publications with MCM7 and Neoplasms
 Carcinoma Antibodies  >51 publications with MCM7 and Carcinoma
 Adenocarcinoma Antibodies  >26 publications with MCM7 and Adenocarcinoma
 Prostatic Neoplasms Antibodies  >17 publications with MCM7 and Prostatic Neoplasms
 Breast Neoplasms Antibodies  >12 publications with MCM7 and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >12 publications with MCM7 and Carcinoma, Squamous Cell
 Disease Models, Animal Antibodies  >10 publications with MCM7 and Disease Models, Animal
 Lung Neoplasms Antibodies  >10 publications with MCM7 and Lung Neoplasms
 Uterine Cervical Neoplasms Antibodies  >9 publications with MCM7 and Uterine Cervical Neoplasms
 Cell Transformation, Neoplastic Antibodies  >8 publications with MCM7 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-MCM7 antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >21 publications with MCM7 and Prostate
 Lung Antibodies  >15 publications with MCM7 and Lung
 Skin Antibodies  >13 publications with MCM7 and Skin
 Vascular Antibodies  >12 publications with MCM7 and Vascular
 Blood Antibodies  >11 publications with MCM7 and Blood
 Liver Antibodies  >9 publications with MCM7 and Liver
 Muscle Antibodies  >9 publications with MCM7 and Muscle
 Placenta Antibodies  >8 publications with MCM7 and Placenta
 Uterus Antibodies  >8 publications with MCM7 and Uterus
 Brain Antibodies  >8 publications with MCM7 and Brain
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