Goat Anti-APOL2 Polyclonal Antibody – Cat# MBS619217

MBS619217(0.03µg/ml) staining of Human Frontal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

APOL2 Antibody – Goat Polyclonal

Name: APOL2 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS619217
Price: 835 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619217

MBS619217 is an antibody targeting APOL2. Also known as APOL2 (Apolipoprotein L2, APOL-II, OTTHUMP00000028936, apolipoprotein L-II). Reactive in Human. Host: Goat. More details

$835 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

APOL2, Polyclonal Antibody

Full Product Name

APOL2 (Apolipoprotein L2, APOL-II, OTTHUMP00000028936, apolipoprotein L-II)

Product Gene Name

anti-APOL2 antibody

Product Synonym Names

Anti -APOL2 (Apolipoprotein L2, APOL-II, OTTHUMP00000028936, apolipoprotein L-II)

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human

Form/Format

Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by affinity chromatography.

Specificity

Recognizes human APOL2.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

37,092 Da

Chromosome Location

Chromosome: 22; NC_000022.10 (36622255..36636000, complement). Location: 22q12

OMIM

607252

3D Structure

ModBase 3D Structure for Q9BQE5

Immunogen

A synthetic peptide from the C-terminus of aa-TKIHEMLQPGQD.

Product Categories/Family for anti-APOL2 antibody

Antibodies; Abs to Lipoproteins

Applications Tested/Suitable for anti-APOL2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-APOL2 antibody

Suitable for use in ELISA.
Dilution: Peptide ELISA: 1:64,000.
Western Blot: 0.03-0.1ug/ml. Approx. 37.1kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 37.1kDa according to NP_112092.1; NP_663612.1). Optimal dilutions to be determined by the researcher.

Other Notes

Small volumes of anti-APOL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for APOL2. It may not necessarily be applicable to this product.

NCBI GI #

22035653

NCBI GeneID

23780

NCBI Accession #

NP_663612.1

UniProt Primary Accession #

Q9BQE5

UniProt Secondary Accession #

O95915; Q59GW9; Q5TH96; Q969T6; Q9BT28; Q9UGT1; Q9UH10; B0QYK7

UniProt Related Accession #

Q9BQE5

GenBank Nucleotide #

NM_145637.1

NCBI Official Full Name

apolipoprotein L2

NCBI Official Synonym Full Names

apolipoprotein L, 2

NCBI Official Symbol

APOL2

NCBI Official Synonym Symbols

APOL3; APOL-II

UniProt Protein Name

Apolipoprotein L2

UniProt Synonym Protein Names

Apolipoprotein L-II

Protein Family

Apolipoprotein

UniProt Gene Name

APOL2

UniProt Entry Name

APOL2_HUMAN

NCBI Protein Information

apolipoprotein L2; OTTHUMP00000198078; OTTHUMP00000198079; OTTHUMP00000198080; OTTHUMP00000235928; apolipoprotein L-II

NCBI Summary for APOL2

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

UniProt Comments for APOL2

APOL2: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles. Belongs to the apolipoprotein L family.

Chromosomal Location of Human Ortholog: 22q12

Cellular Component: endoplasmic reticulum membrane; membrane; extracellular region

Molecular Function: lipid binding; high-density lipoprotein binding; receptor binding

Biological Process: cholesterol metabolic process; maternal process involved in pregnancy; multicellular organismal development; acute-phase response; lipoprotein metabolic process; lipid metabolic process; lipid transport

Disease: Schizophrenia

Research Articles on APOL2

1. Results reveal a novel function for ApoL2 in conferring anti-apoptotic ability of human bronchial epithelium to the cytotoxic effects of IFN-gamma, in maintaining airway epithelial layer integrity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-APOL2 antibody

Disease Name	Pubmed Publications
Schizophrenia Antibodies	>1 publications with APOL2 and Schizophrenia

Organs/Tissues associated with anti-APOL2 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>2 publications with APOL2 and Lung
Skin Antibodies	>1 publications with APOL2 and Skin
Liver Antibodies	>1 publications with APOL2 and Liver
Vascular Antibodies	>1 publications with APOL2 and Vascular
Pancreas Antibodies	>1 publications with APOL2 and Pancreas
Blood Antibodies	>1 publications with APOL2 and Blood
Placenta Antibodies	>1 publications with APOL2 and Placenta
Prostate Antibodies	>1 publications with APOL2 and Prostate
Spleen Antibodies	>1 publications with APOL2 and Spleen
Muscle Antibodies	>1 publications with APOL2 and Muscle