Rabbit Anti-ZNF350 Polyclonal Antibody – Cat# MBS619807

Western blot analysis of ZBRK1 in A-20 lysate with ZBRK1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Zinc Finger Protein 350 (ZNF350) Antibody – Rabbit Polyclonal

Name: ZNF350 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS619807
Price: 850 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619807

ZBRK1 is a member of the Kruppel-associated box-zinc finger protein (KRAB-ZFP) protein family of transcriptional repressors. ZBRK1 has been shown to not only be up-regulated in senescent fibroblasts but also interacts with BRCA1, a transcriptional regulator… More details

$850 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Zinc finger protein 350 (ZNF350), Polyclonal Antibody

Full Product Name

Zinc finger protein 350 (ZBRK1, ZNF350, KRAB zinc finger protein ZFQR, ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc-finger protein ZBRK1)

Product Gene Name

anti-ZNF350 antibody

Product Synonym Names

Anti -Zinc finger protein 350 (ZBRK1, ZNF350, KRAB zinc finger protein ZFQR, ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc-finger protein ZBRK1)

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Supplied as a liquid in PBS, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human ZBRK1. Species Crossreactivity: Mouse and rat.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

60,011 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (52467593..52490079, complement). Location: 19q13.41

OMIM

605422

3D Structure

ModBase 3D Structure for Q9GZX5

Immunogen

Synthetic peptide corresponding to 20aa from near the carboxy terminus of the human ZBRK1.

Positive Control

A20 Cell Lysate

Product Categories/Family for anti-ZNF350 antibody

Antibodies; Abs to Transcription Factors; Zinc (Ring) Finger

Applications Tested/Suitable for anti-ZNF350 antibody

Western Blot (WB)

Application Notes for anti-ZNF350 antibody

Suitable for use in Western Blot.
Dilution: Western Blot: 1-2ug/ml

Other Notes

Small volumes of anti-ZNF350 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZNF350 purchase

MBS619807 is an antibody targeting ZNF350. Also known as Zinc finger protein 350 (ZBRK1, ZNF350, KRAB zinc finger protein ZFQR, ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc-finger protein ZBRK1). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZNF350. It may not necessarily be applicable to this product.

NCBI GI #

59710107

NCBI GeneID

59348

NCBI Accession #

NP_067645.3

UniProt Primary Accession #

Q9GZX5

UniProt Secondary Accession #

Q96G73; Q9HAQ4

UniProt Related Accession #

Q9GZX5

GenBank Nucleotide #

NM_021632.3

NCBI Official Full Name

zinc finger protein 350

NCBI Official Synonym Full Names

zinc finger protein 350

NCBI Official Symbol

ZNF350

NCBI Official Synonym Symbols

ZFQR; ZBRK1

UniProt Protein Name

Zinc finger protein 350

UniProt Synonym Protein Names

KRAB zinc finger protein ZFQR; Zinc finger and BRCA1-interacting protein with a KRAB domain 1; Zinc finger protein ZBRK1

Protein Family

Zinc finger protein

UniProt Gene Name

ZNF350

UniProt Synonym Gene Names

ZBRK1

UniProt Entry Name

ZN350_HUMAN

NCBI Protein Information

zinc finger protein 350; zinc finger protein ZBRK1; zinc-finger protein ZBRK1; KRAB zinc finger protein ZFQR; zinc finger and BRCA1-interacting protein with a KRAB domain 1

UniProt Comments for ZNF350

ZNF350: Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: Transcription factor; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: nucleoplasm; nuclear matrix; transcriptional repressor complex; nucleus

Molecular Function: protein binding; DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent

Research Articles on ZNF350

1. KRAB-containing zinc-finger transcriptional regulator, ZBRK1, an interaction partner of the SCA2 gene product ataxin-2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZNF350 antibody

Reference Product	PubMed Publications
BRCA1 antibody	>18 publications with ZNF350 and BRCA1

Pathways associated with anti-ZNF350 antibody

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram

Diseases associated with anti-ZNF350 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>18 publications with ZNF350 and Neoplasms
Breast Neoplasms Antibodies	>10 publications with ZNF350 and Breast Neoplasms
Genetic Predisposition to Disease Antibodies	>7 publications with ZNF350 and Genetic Predisposition to Disease
Nervous System Diseases Antibodies	>3 publications with ZNF350 and Nervous System Diseases
Mental Disorders Antibodies	>2 publications with ZNF350 and Mental Disorders
Genomic Instability Antibodies	>1 publications with ZNF350 and Genomic Instability

Organs/Tissues associated with anti-ZNF350 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>6 publications with ZNF350 and Testis
Muscle Antibodies	>4 publications with ZNF350 and Muscle
Embryonic Tissue Antibodies	>3 publications with ZNF350 and Embryonic Tissue
Blood Antibodies	>3 publications with ZNF350 and Blood
Placenta Antibodies	>3 publications with ZNF350 and Placenta
Liver Antibodies	>3 publications with ZNF350 and Liver
Brain Antibodies	>3 publications with ZNF350 and Brain
Kidney Antibodies	>2 publications with ZNF350 and Kidney
Pancreas Antibodies	>2 publications with ZNF350 and Pancreas
Prostate Antibodies	>2 publications with ZNF350 and Prostate