Goat Anti-AGAP1 Polyclonal Antibody – Cat# MBS620181

AGAP1 Antibody – Goat Polyclonal

Name: AGAP1 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS620181
Price: 705 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620181

GTPase-activating protein for the ADP ribosylation factor family (potential). Overexpression inhibits formation of platelet-derived growth factor-induced ruffles and also induced loss of actin stress fibers. More details

$705 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AGAP1, Polyclonal Antibody

Full Product Name

AGAP1 (CENTG2, GGAP1, KIAA1099, Centaurin, gamma 2, GTP-binding and GTPase-activating Protein 1, Arf GAP with GTP-binding Protein-like, ANK Repeat and PH domains 1)

Product Gene Name

anti-AGAP1 antibody

Product Synonym Names

Anti -AGAP1 (CENTG2, GGAP1, KIAA1099, Centaurin, gamma 2, GTP-binding and GTPase-activating Protein 1, Arf GAP with GTP-binding Protein-like, ANK Repeat and PH domains 1)

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human

Form/Format

Supplied as a liquid in 0.5 mg/ml, tris-saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human AGAP1.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

94,470 Da

Chromosome Location

Chromosome: 2; NC_000002.11 (236402733..237040444). Location: 2q37

OMIM

608651

3D Structure

ModBase 3D Structure for Q9UPQ3

Immunogen

Synthetic peptide corresponding to human AGAP1.

Product Categories/Family for anti-AGAP1 antibody

Antibodies; Abs to Transport Proteins

Applications Tested/Suitable for anti-AGAP1 antibody

ELISA (EL/EIA)

Application Notes for anti-AGAP1 antibody

Suitable for use in ELISA.
Dilution: ELISA: 1:4000

Other Notes

Small volumes of anti-AGAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGAP1 purchase

MBS620181 is an antibody targeting AGAP1. Also known as AGAP1 (CENTG2, GGAP1, KIAA1099, Centaurin, gamma 2, GTP-binding and GTPase-activating Protein 1, Arf GAP with GTP-binding Protein-like, ANK Repeat and PH domains 1). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for AGAP1. It may not necessarily be applicable to this product.

NCBI GI #

349585207

NCBI GeneID

116987

NCBI Accession #

NP_001231817.1

UniProt Primary Accession #

Q9UPQ3

UniProt Secondary Accession #

Q541S5; Q6P9D7; Q9NV93; B2RTX7

UniProt Related Accession #

Q9UPQ3

GenBank Nucleotide #

NM_001244888.1

NCBI Official Full Name

arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform 3

NCBI Official Synonym Full Names

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

NCBI Official Symbol

AGAP1

NCBI Official Synonym Symbols

GGAP1; AGAP-1; CENTG2; cnt-g2

UniProt Protein Name

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

UniProt Synonym Protein Names

Centaurin-gamma-2; Cnt-g2; GTP-binding and GTPase-activating protein 1

Protein Family

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein

UniProt Gene Name

AGAP1

UniProt Synonym Gene Names

CENTG2; KIAA1099; AGAP-1; Cnt-g2; GGAP1

UniProt Entry Name

AGAP1_HUMAN

NCBI Protein Information

arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1; centaurin, gamma 2; GTP-binding and GTPase-activating protein 1; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1

NCBI Summary for AGAP1

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

UniProt Comments for AGAP1

CENTG2: GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. Belongs to the centaurin gamma-like family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, ARF

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: cytoplasm

Molecular Function: GTP binding; zinc ion binding; phospholipid binding

Biological Process: protein transport; small GTPase mediated signal transduction; positive regulation of GTPase activity

Research Articles on AGAP1

1. GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AGAP1 antibody

Reference Product	PubMed Publications
ARF1 antibody	>7 publications with AGAP1 and ARF1
ARF6 antibody	>2 publications with AGAP1 and ARF6
LAMP1 antibody	>1 publications with AGAP1 and LAMP1
ARF5 antibody	>1 publications with AGAP1 and ARF5
MAP9 antibody	>1 publications with AGAP1 and MAP9

Pathways associated with anti-AGAP1 antibody

Products by Pathway	Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram

Diseases associated with anti-AGAP1 antibody

Disease Name	Pubmed Publications
Lymphoma Antibodies	>1 publications with AGAP1 and Lymphoma
Immune System Diseases Antibodies	>1 publications with AGAP1 and Immune System Diseases
Neoplasms Antibodies	>1 publications with AGAP1 and Neoplasms
Autistic Disorder Antibodies	>1 publications with AGAP1 and Autistic Disorder

Organs/Tissues associated with anti-AGAP1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with AGAP1 and Blood
Brain Antibodies	>1 publications with AGAP1 and Brain