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Macrophage Inflammatory Protein-1a (CCL4L1) Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS621030

MIP-1 alpha is a member of the CC chemokine family of proteins which have been shown to be produced by numerous cell types including activated T cells, B cells, monocytes, mast cells and endothelial cells. MIP-1a acts as a monocyte chemoattractant and has… More details

$865 / 1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Macrophage Inflammatory Protein-1a (CCL4L1), Polyclonal Antibody
Full Product Name
Macrophage Inflammatory Protein-1a (MIP-1a)
Product Gene Name
Product Synonym Names
Anti -Macrophage Inflammatory Protein-1a (MIP-1a)
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Human
Form/Format
Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.
Purity/Purification
Purified
Purified
Specificity
Recognizes human MIP-1a.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
10,166 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (34538468..34540275). Location: 17q12
OMIM
603782
3D Structure
ModBase 3D Structure for Q8NHW4
Immunogen
Recombinant corresponding to aa27-92 from human MIP-1, fused to 6x His-tag at N-terminal, expressed in E. coli.
Applications Tested/Suitable for anti-CCL4L1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Gel Shift Assay (GS/EMSA)
Application Notes for anti-CCL4L1 antibody
Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry, Immunoassays, development of rapid tests and other antibody recognition assays.

Other Notes

Small volumes of anti-CCL4L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL4L1 purchase

MBS621030 is an antibody targeting CCL4L1. Also known as Macrophage Inflammatory Protein-1a (MIP-1a). Reactive in Human. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL4L1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
macrophage inflammatory protein-1b2
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 4-like 1
NCBI Official Symbol
CCL4L1
NCBI Official Synonym Symbols
LAG1; CCL4L; LAG-1; SCYA4L; AT744.2
UniProt Protein Name
C-C motif chemokine 4-like
UniProt Synonym Protein Names
Lymphocyte activation gene 1 protein; LAG-1; Macrophage inflammatory protein 1-beta; MIP-1-beta; Monocyte adherence-induced protein 5-alpha; Small-inducible cytokine A4-like
Protein Family
UniProt Gene Name
CCL4L1
UniProt Synonym Gene Names
CCL4L; LAG1; SCYA4L1; LAG-1; MIP-1-beta
UniProt Entry Name
CC4L_HUMAN
NCBI Protein Information
C-C motif chemokine 4-like; MIP-1-beta; macrophage inflammatory protein-1b2; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; monocyte adherence-induced protein 5-alpha

NCBI Summary for CCL4L1

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to CCL4 which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for CCL4L1

CCL4L1: Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5. Belongs to the intercrine beta (chemokine CC) family. 10 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted; Chemokine

Chromosomal Location of Human Ortholog: 17q12
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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