Smallpox B5R Antibody – Rabbit Polyclonal

B5R, a 561 amino acid membrane protein containing ankyrin repeats that mediate protein-protein interactions and is related to the regulators of complement activation (RCA) superfamily. It consists of four short consensus repeats (SCRs) and transmembrane anchor region or the CT (cytoplasmic tail). Its transmembrane domain is the major determinant for targeting the B5R protein to the outer membrane of EEV (extracellular enveloped virus) and for supporting EEV formation, thus playing an important role in the process of virus envelopment and release. It may also be involved in viral evasion from host immune responses. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, incorporation of the protein into EEV and for EEV formation.

Small volumes of anti-Smallpox B5R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS621252 is an antibody targeting Smallpox B5R. Reactive in Bovine, Human. Host: Rabbit.