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Vasoactive Intestinal Polypeptide Receptor 2 (VIPR2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS621410

Vasoactive intestinal peptide (VIP) is a 28-aminoacid peptide (human, chr 6q26-q27). Expressed and secreted by neurons innervating primary and secondary immune organs such as lymph nodes with a Mol.wt of 20kD. VIP is a potent neurotrophic factor causes… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Vasoactive intestinal Polypeptide Receptor 2 (VIPR2), Polyclonal Antibody
Full Product Name
Vasoactive intestinal Polypeptide Receptor 2 (VIP Receptor 2, VIP2R, VIPR2, Helodermin Preferring VIP Receptor, Helodermin-preferring VIP Receptor, Pituitary Adenylate Cyclase Activating Polypeptide Type III Receptor, PACAP Type III Receptor, VPAC2, VPAC2
Product Gene Name
anti-VIPR2 antibody
Product Synonym Names
Anti -Vasoactive intestinal Polypeptide Receptor 2 (VIP Receptor 2, VIP2R, VIPR2, Helodermin Preferring VIP Receptor, Helodermin-preferring VIP Receptor, Pituitary Adenylate Cyclase Activating Polypeptide Type III Receptor, PACAP Type III Receptor, VPAC2, VPAC2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder. Reconstitute with sterile dH2O.
Purity/Purification
Serum
Serum
Specificity
Recognizes human Vasoactive Intestinal Peptide-Receptor 2
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
49,479 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (158820866..158937649, complement). Location: 7q36.3
OMIM
601970
3D Structure
ModBase 3D Structure for P41587
Immunogen
Synthetic human VIP-R2 (aa 3-14) (RFHLEIQEEETK)

Product Categories/Family for anti-VIPR2 antibody

Antibodies; Abs to Receptors
Applications Tested/Suitable for anti-VIPR2 antibody
ELISA (EL/EIA)
Application Notes for anti-VIPR2 antibody
Suitable for use in ELISA.

Other Notes

Small volumes of anti-VIPR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VIPR2 purchase

MBS621410 is an antibody targeting VIPR2. Also known as Vasoactive intestinal Polypeptide Receptor 2 (VIP Receptor 2, VIP2R, VIPR2, Helodermin Preferring VIP Receptor, Helodermin-preferring VIP Receptor, Pituitary Adenylate Cyclase Activating Polypeptide Type III Receptor, PACAP Type III Receptor, VPAC2, VPAC2. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VIPR2. It may not necessarily be applicable to this product.

NCBI GI #
21361557
NCBI GeneID
7434
NCBI Accession #
NP_003373.2
UniProt Primary Accession #
P41587
UniProt Secondary Accession #
Q13053; Q15870; Q53Y09; Q9UCW0
UniProt Related Accession #
P41587; Q6ZN22; Q71V81
GenBank Nucleotide #
NM_003382.4
NCBI Official Full Name
vasoactive intestinal polypeptide receptor 2
NCBI Official Synonym Full Names
vasoactive intestinal peptide receptor 2
NCBI Official Symbol
VIPR2
NCBI Official Synonym Symbols
VPAC2; SCZD16; VPCAP2R; FLJ16511
UniProt Protein Name
Vasoactive intestinal polypeptide receptor 2
UniProt Synonym Protein Names
Helodermin-preferring VIP receptor; Pituitary adenylate cyclase-activating polypeptide type III receptor
Protein Family
Vasoactive intestinal polypeptide receptor
UniProt Gene Name
VIPR2
UniProt Synonym Gene Names
VIP2R
UniProt Entry Name
VIPR2_HUMAN
NCBI Protein Information
vasoactive intestinal polypeptide receptor 2; VIP-R-2; PACAP-R3; PACAP-R-3; OTTHUMP00000200015; OTTHUMP00000200016; OTTHUMP00000200017; PACAP type III receptor; helodermin-preferring VIP receptor; pituitary adenylate cyclase-activating polypeptide type III receptor

NCBI Summary for VIPR2

Vasoactive intestinal peptide (VIP; MIM 192320) and pituitary adenylate cyclase activating polypeptide (PACAP; MIM 102980) are homologous peptides that function as neurotransmitters and neuroendocrine hormones. While the receptors for VIP and PACAP share homology, they differ in their substrate specificities and expression patterns. See VIPR1 (MIM 192321) and ADCYAP1R1(MIM 102981).[supplied by OMIM]
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UniProt Comments for VIPR2

VIPR2: This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 2

Chromosomal Location of Human Ortholog: 7q36.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; vasoactive intestinal polypeptide receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; negative regulation of smooth muscle cell proliferation; adenylate cyclase activation; signal transduction
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Research Articles on VIPR2

1. VPAC(2) receptor presents an extranuclear localization and its protein expression is lower than that of VPAC(1) receptor in human breast tissue samples

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VIPR2 antibody

 Reference Product  PubMed Publications
 VIP antibody  >96 publications with VIPR2 and VIP
 ADCYAP1 antibody  >42 publications with VIPR2 and ADCYAP1

Pathways associated with anti-VIPR2 antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with anti-VIPR2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with VIPR2 and Inflammation
 Lung Diseases Antibodies  >5 publications with VIPR2 and Lung Diseases
 Breast Neoplasms Antibodies  >4 publications with VIPR2 and Breast Neoplasms
 Schizophrenia Antibodies  >4 publications with VIPR2 and Schizophrenia
 Prostatic Neoplasms Antibodies  >3 publications with VIPR2 and Prostatic Neoplasms
 Lung Neoplasms Antibodies  >3 publications with VIPR2 and Lung Neoplasms
 Liver Neoplasms Antibodies  >2 publications with VIPR2 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >2 publications with VIPR2 and Liver Neoplasms, Experimental
 Arthritis, Rheumatoid Antibodies  >2 publications with VIPR2 and Arthritis, Rheumatoid
 Pancreatic Neoplasms Antibodies  >2 publications with VIPR2 and Pancreatic Neoplasms

Organs/Tissues associated with anti-VIPR2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >48 publications with VIPR2 and Brain
 Heart Antibodies  >9 publications with VIPR2 and Heart
 Prostate Antibodies  >7 publications with VIPR2 and Prostate
 Eye Antibodies  >6 publications with VIPR2 and Eye
 Embryonic Tissue Antibodies  >5 publications with VIPR2 and Embryonic Tissue
 Thymus Antibodies  >4 publications with VIPR2 and Thymus
 Testis Antibodies  >4 publications with VIPR2 and Testis
 Connective Tissue Antibodies  >3 publications with VIPR2 and Connective Tissue
 Uterus Antibodies  >3 publications with VIPR2 and Uterus
 Placenta Antibodies  >1 publications with VIPR2 and Placenta
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