Rabbit Anti-HSPH1 Polyclonal Antibody – Cat# MBS621634

Heat Shock Protein 110 (HSPH1) Antibody – Rabbit Polyclonal

Name: HSPH1 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS621634
Price: 725 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS621634

Hsp110 belongs to a family of large stress proteins known as the Hsp110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied Hsp70 family. They share 30-33% amino acid identity, mostly in the conserved ATP-binding… More details

$725 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Heat Shock Protein 110 (Hsph1), Polyclonal Antibody

Full Product Name

Heat Shock Protein 110 (HSP110)

Product Gene Name

anti-Hsph1 antibody

Product Synonym Names

Anti -Heat Shock Protein 110 (HSP110)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Bovine, Hamster, Human, Monkey, Mouse, Rat, Sheep, Yeast

Form/Format

Supplied as a liquid in PBS, pH7.2, 50% glycerol and 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes hamster hsp110. Species Crossreactivity: human, monkey, rat, mouse, bovine, sheep, yeast.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

96,407 Da

Chromosome Location

Chromosome: 5; NC_000071.6 (149616845..149636315, complement). Location: 5 G3; 5 89.18 cM

3D Structure

ModBase 3D Structure for Q61699

Immunogen

Synthetic peptide derived from the sequence of hamster Hsp110; sequence identical to human and mouse.

Product Categories/Family for anti-Hsph1 antibody

Antibodies; Abs to Heat Shock Proteins

Applications Tested/Suitable for anti-Hsph1 antibody

Western Blot (WB)

Application Notes for anti-Hsph1 antibody

Suitable for use in Western Blot.
Dilution: Western Blot:1:1000

Other Notes

Small volumes of anti-Hsph1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Hsph1 purchase

MBS621634 is an antibody targeting Hsph1. Also known as Heat Shock Protein 110 (HSP110). Reactive in Bovine, Hamster, Human, Monkey, Mouse, Rat, Sheep, Yeast. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Hsph1. It may not necessarily be applicable to this product.

NCBI GI #

114145505

NCBI GeneID

15505

NCBI Accession #

NP_038587.2

UniProt Primary Accession #

Q61699

UniProt Secondary Accession #

Q3TNS2; Q3UIY8; Q62578; Q62579; Q6A0A5; Q8C430; Q8VCW6

UniProt Related Accession #

Q61699

GenBank Nucleotide #

NM_013559.2

NCBI Official Full Name

heat shock protein 105 kDa

NCBI Official Synonym Full Names

heat shock 105kDa/110kDa protein 1

NCBI Official Symbol

Hsph1

NCBI Official Synonym Symbols

105kDa; Hsp105; Hsp110; hsp-E7I; AI790491

UniProt Protein Name

Heat shock protein 105 kDa

UniProt Synonym Protein Names

42 degrees C-HSP; Heat shock 110 kDa protein; Heat shock-related 100 kDa protein E7I

Protein Family

Heat shock protein

UniProt Gene Name

Hsph1

UniProt Synonym Gene Names

Hsp105; Hsp110; Kiaa0201; HSP-E7I

UniProt Entry Name

HS105_MOUSE

NCBI Protein Information

heat shock protein 105 kDa; HSP105 42 C-HSP; 42 degrees C-HSP; heat shock protein 110; heat shock 110 kDa protein; heat shock protein, 105 kDa; heat shock-related 100 kDa protein E7I

UniProt Comments for Hsph1

HSP105: a molecular chaperone of the heat shock protein 70 family. Has ATPase activity. Expressed at especially high levels in mammalian brain and has been shown to suppress apoptosis in neuronal cells and to prevent the aggregation of proteins following heat shock. Known to interact with a variety of proteins including alpha-tubulin and the androgen receptor. Two alternatively spliced isoforms have been described.

Protein type: Chaperone; Heat shock protein

Cellular Component: nucleoplasm; microtubule; cytoplasm; extracellular region; cytosol; nucleus

Molecular Function: protein binding; nucleotide binding; ATP binding; alpha-tubulin binding

Biological Process: positive regulation of NK T cell activation; chaperone cofactor-dependent protein folding; positive regulation of MHC class I biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron apoptosis; response to unfolded protein

Research Articles on Hsph1

1. Hsp105 may play an important role in the refolding of denatured proteins and protection against stress-induced cell death in mammalian cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Hsph1 antibody

Products by Pathway	Pathway Diagram
Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies	Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Scavenging By Class F Receptors Pathway antibodies	Scavenging By Class F Receptors Pathway Diagram

Diseases associated with anti-Hsph1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>15 publications with Hsph1 and Neoplasms
Adenocarcinoma Antibodies	>6 publications with Hsph1 and Adenocarcinoma
Disease Models, Animal Antibodies	>3 publications with Hsph1 and Disease Models, Animal
Inflammation Antibodies	>3 publications with Hsph1 and Inflammation
Cardiovascular Diseases Antibodies	>2 publications with Hsph1 and Cardiovascular Diseases
Brain Diseases Antibodies	>2 publications with Hsph1 and Brain Diseases
Nervous System Diseases Antibodies	>2 publications with Hsph1 and Nervous System Diseases
Necrosis Antibodies	>2 publications with Hsph1 and Necrosis
Cell Transformation, Neoplastic Antibodies	>1 publications with Hsph1 and Cell Transformation, Neoplastic
Fibrosis Antibodies	>1 publications with Hsph1 and Fibrosis

Organs/Tissues associated with anti-Hsph1 antibody

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>7 publications with Hsph1 and Skin
Brain Antibodies	>6 publications with Hsph1 and Brain
Blood Antibodies	>5 publications with Hsph1 and Blood
Testis Antibodies	>3 publications with Hsph1 and Testis
Lymph Node Antibodies	>3 publications with Hsph1 and Lymph Node
Intestine Antibodies	>2 publications with Hsph1 and Intestine
Lung Antibodies	>2 publications with Hsph1 and Lung
Tongue Antibodies	>1 publications with Hsph1 and Tongue
Ovary Antibodies	>1 publications with Hsph1 and Ovary
Pancreas Antibodies	>1 publications with Hsph1 and Pancreas