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ASCL3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6237259

Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]). [supplied by OMIM] More details

$960 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASCL3, Monoclonal Antibody
Full Product Name
ASCL3 (Achaete-scute Complex Homolog 3 (Drosophila), HASH3, SGN1, bHLHa42) (MaxLight 750)
Product Gene Name
Product Synonym Names
Achaete-scute Complex Homolog 3 (Drosophila); HASH3; SGN1; bHLHa42
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2F8
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified
Specificity
Recognizes ASCL3.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
20,797 Da
OMIM
609154
3D Structure
ModBase 3D Structure for Q9NQ33
Immunogen
ASCL3 (NP_065697.1, 1aa-95aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFT
Conjugate
MaxLight750
Applications Tested/Suitable for anti-ASCL3 antibody
FLISA, Western Blot (WB)
Application Notes for anti-ASCL3 antibody
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-ASCL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASCL3 purchase

MBS6237259 is an antibody targeting ASCL3. Also known as ASCL3 (Achaete-scute Complex Homolog 3 (Drosophila), HASH3, SGN1, bHLHa42) (MaxLight 750). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ASCL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
achaete-scute homolog 3
NCBI Official Synonym Full Names
achaete-scute family bHLH transcription factor 3
NCBI Official Symbol
ASCL3
NCBI Official Synonym Symbols
SGN1; HASH3; bHLHa42
UniProt Protein Name
Achaete-scute homolog 3
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 42; bHLHa42; bHLH transcriptional regulator Sgn-1
Protein Family
UniProt Gene Name
ASCL3
UniProt Synonym Gene Names
BHLHA42; HASH3; SGN1; ASH-3; hASH3; bHLHa42
UniProt Entry Name
ASCL3_HUMAN
NCBI Protein Information
achaete-scute homolog 3; achaete-scute complex homolog 3; bHLH transcriptional regulator Sgn-1; class A basic helix-loop-helix protein 42; bHLH transcription factor Sgn-1 (Salivary Glands 1)

UniProt Comments for ASCL3

ASCL3: Transcriptional repressor. Inhibits myogenesis.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 11p15.3

Cellular Component: transcription factor complex; nucleus

Molecular Function: protein dimerization activity; DNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ASCL3 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with ASCL3 and Carcinoma
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