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STX3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS625569

STX3 is otentially involved in docking of synaptic vesicles at presynaptic active zones. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STX3, Polyclonal Antibody
Full Product Name
STX3, ID (Syntaxin-3, STX3A)
Product Gene Name
anti-STX3 antibody
Product Synonym Names
Anti -STX3, ID (Syntaxin-3, STX3A)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human STX3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
33,155 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (59522532..59573355). Location: 11q12.1
OMIM
600876
3D Structure
ModBase 3D Structure for Q13277
Immunogen
Synthetic peptide selected from the Center region of human STX3 (KLH).

Product Categories/Family for anti-STX3 antibody

Antibodies; Abs to Syntaxin; Synaptotagmin; Synaptophysin
Applications Tested/Suitable for anti-STX3 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-STX3 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100

Immunohistochemistry (IHC) of anti-STX3 antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with STX3 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-STX3 Polyclonal Antibody – Cat# MBS625569

Western Blot (WB) of anti-STX3 antibody

Western blot analysis of anti-STX3 Antibody (Center) in A375 cell line lysates (35ug/lane). STX3(arrow) was detected using the purified Pab.
Rabbit Anti-STX3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS625569

Western Blot (WB) of anti-STX3 antibody

Western blot analysis of STX3 (arrow) using rabbit polyclonal STX3 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the STX3 gene.
Rabbit Anti-STX3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS625569

Other Notes

Small volumes of anti-STX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STX3 purchase

MBS625569 is an antibody targeting STX3. Also known as STX3, ID (Syntaxin-3, STX3A). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STX3. It may not necessarily be applicable to this product.

NCBI GI #
295842492
NCBI GeneID
6809
NCBI Accession #
NP_001171511.1
UniProt Primary Accession #
Q13277
UniProt Secondary Accession #
O43750; O43751; Q15360
UniProt Related Accession #
Q13277; Q53YE2; Q7Z338
GenBank Nucleotide #
NM_001178040.1
NCBI Official Full Name
syntaxin-3 isoform 2
NCBI Official Synonym Full Names
syntaxin 3
NCBI Official Symbol
STX3
NCBI Official Synonym Symbols
STX3A; FLJ30906
UniProt Protein Name
Syntaxin-3
Protein Family
Syntaxin
UniProt Gene Name
STX3
UniProt Synonym Gene Names
STX3A
UniProt Entry Name
STX3_HUMAN
NCBI Protein Information
syntaxin-3; syntaxin 3A; OTTHUMP00000235765; OTTHUMP00000235767; OTTHUMP00000235768

NCBI Summary for STX3

The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
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UniProt Comments for STX3

STX3: Potentially involved in docking of synaptic vesicles at presynaptic active zones. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: SNARE complex; specific granule; azurophil granule; synaptic vesicle; neuron projection; growth cone; lamellipodium; dendrite; apical plasma membrane; plasma membrane; integral to membrane; vacuole; intercellular junction

Molecular Function: arachidonic acid binding; SNAP receptor activity; SNARE binding; protein binding

Biological Process: synaptic vesicle fusion to presynaptic membrane; intracellular protein transport; positive regulation of cell adhesion; vesicle docking; positive regulation of chemotaxis; positive regulation of cell proliferation; neurite development
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Research Articles on STX3

1. syntaxin 3 interacts with CFTR in vivo.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STX3 antibody

 Reference Product  PubMed Publications
 VAMP8 antibody  >2 publications with STX3 and VAMP8
 SNAP23 antibody  >2 publications with STX3 and SNAP23
 VAMP3 antibody  >1 publications with STX3 and VAMP3

Pathways associated with anti-STX3 antibody

 Products by Pathway  Pathway Diagram
 Botulinum Neurotoxicity Pathway antibodies  Botulinum Neurotoxicity Pathway Diagram
 Proteolytic Cleavage Of SNARE Complex Proteins Pathway antibodies  Proteolytic Cleavage Of SNARE Complex Proteins Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram

Diseases associated with anti-STX3 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with STX3 and Congenital Abnormalities
 Inflammation Antibodies  >1 publications with STX3 and Inflammation
 Cholestasis Antibodies  >1 publications with STX3 and Cholestasis
 Fibrosis Antibodies  >1 publications with STX3 and Fibrosis

Organs/Tissues associated with anti-STX3 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >5 publications with STX3 and Bone
 Vascular Antibodies  >1 publications with STX3 and Vascular
 Blood Antibodies  >1 publications with STX3 and Blood
 Nerve Antibodies  >1 publications with STX3 and Nerve
 Liver Antibodies  >1 publications with STX3 and Liver
 Kidney Antibodies  >1 publications with STX3 and Kidney
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