Rabbit Anti-ACOT11 Polyclonal Antibody – Cat# MBS6270974

ACOT11 Antibody – Rabbit Polyclonal

Name: ACOT11 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6270974
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6270974

This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low… More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ACOT11, Polyclonal Antibody

Full Product Name

ACOT11, CT (ACOT11, BFIT, KIAA0707, THEA, Acyl-coenzyme A thioesterase 11, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase) (MaxLight 405)

Product Gene Name

anti-ACOT11 antibody

Product Synonym Names

ACOT11; BFIT; KIAA0707; THEA; Acyl-coenzyme A thioesterase 11; Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

67,152 Da

OMIM

606803

3D Structure

ModBase 3D Structure for Q8WXI4

Immunogen

ACOT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-583 amino acids from the C-terminal region of human ACOT11.

Conjugate

MaxLight405

Note

Preservative Free

Product Categories/Family for anti-ACOT11 antibody

Antibodies; Coenzyme A

Applications Tested/Suitable for anti-ACOT11 antibody

Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)

Application Notes for anti-ACOT11 antibody

FC/FACS: 1:10-50
FLISA: 1:1,000
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-ACOT11 antibody

Kirkby, B., et al. Prog. Lipid Res. 49(4):366-377(2010). Hunt, M.C., et al. J. Lipid Res. 46(9):2029-2032(2005). Adams, S.H., et al. Biochem. J. 360 (PT 1), 135-142 (2001).

Other Notes

Small volumes of anti-ACOT11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACOT11 purchase

MBS6270974 is an antibody targeting ACOT11. Also known as ACOT11, CT (ACOT11, BFIT, KIAA0707, THEA, Acyl-coenzyme A thioesterase 11, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ACOT11. It may not necessarily be applicable to this product.

NCBI GI #

22165355

NCBI GeneID

26027

NCBI Accession #

NP_056362.1

NCBI Related Accession #

NP_671517.1

UniProt Primary Accession #

Q8WXI4

UniProt Secondary Accession #

O75187; Q52LP1; Q53ER9; Q96DI1; Q9H883; B1AQ22; D3DQ50

UniProt Related Accession #

Q8WXI4

GenBank Nucleotide #

NM_015547.3

NCBI Official Full Name

acyl-coenzyme A thioesterase 11 isoform 1

NCBI Official Synonym Full Names

acyl-CoA thioesterase 11

NCBI Official Symbol

ACOT11

NCBI Official Synonym Symbols

BFIT; THEA; THEM1; STARD14

UniProt Protein Name

Acyl-coenzyme A thioesterase 11

UniProt Synonym Protein Names

Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase; BFIT

Protein Family

Acyl-coenzyme A thioesterase

UniProt Gene Name

ACOT11

UniProt Synonym Gene Names

BFIT; KIAA0707; THEA; Acyl-CoA thioesterase 11; BFIT

UniProt Entry Name

ACO11_HUMAN

NCBI Protein Information

acyl-coenzyme A thioesterase 11; START domain containing 14; StAR-related lipid transfer (START) domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; thioesterase superfamily member 1; t

UniProt Comments for ACOT11

ACOT11: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.1.2.-

Chromosomal Location of Human Ortholog: 1p32.3

Cellular Component: cytoplasm

Molecular Function: acyl-CoA hydrolase activity; lipid binding

Biological Process: response to temperature stimulus; response to cold; fatty acid metabolic process

Research Articles on ACOT11

1. The N-terminal region of human fat inducible thioesterase variant 2 constitutes a mitochondrial location signal sequence, which undergoes mitochondrion-dependent posttranslational cleavage.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ACOT11 antibody

Disease Name	Pubmed Publications
Insulin Resistance Antibodies	>1 publications with ACOT11 and Insulin Resistance
Fatty Liver Antibodies	>1 publications with ACOT11 and Fatty Liver
Inflammation Antibodies	>1 publications with ACOT11 and Inflammation

Organs/Tissues associated with anti-ACOT11 antibody

Organ/Tissue Name	Pubmed Publications
Adipose Tissue Antibodies	>4 publications with ACOT11 and Adipose Tissue