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DUSP13 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS627164

Dual-specificity phosphatases, a subfamily of protein-tyrosine phosphatases, play important roles in signal transduction, cell cycle progression, and tumor suppression. The cDNA encoding a novel phosphatase, PIR1, phosphatase that interacts with RNA/RNP… More details

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Product Overview

Online Datasheet in PDF
Product Name
DUSP13, Polyclonal Antibody
Full Product Name
DUSP13, NT (M1) (Dual Specificity Protein Phosphatase 13, Testis-and Skeletal-muscle-specific DSP, Dual Specificity Phosphatase SKRP4, TMDP)
Product Gene Name
Product Synonym Names
Anti -DUSP13, NT (M1) (Dual Specificity Protein Phosphatase 13, Testis-and Skeletal-muscle-specific DSP, Dual Specificity Phosphatase SKRP4, TMDP)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human DUSP13-M1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
22,149 Da
OMIM
613191
3D Structure
ModBase 3D Structure for Q9UII6
Immunogen
Synthetic peptide selected from the N-terminal region of human DUSP13-M1 protein (KLH).
Applications Tested/Suitable for anti-DUSP13 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-DUSP13 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-DUSP13 antibody

Western blot analysis of DUSP13 (arrow) using DUSP13-M1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DUSP13 gene (Lane 2) (Origene Technologies).
Rabbit Anti-DUSP13 Polyclonal Antibody – Cat# MBS627164

Immunohistochemistry (IHC) of anti-DUSP13 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-DUSP13 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS627164

Other Notes

Small volumes of anti-DUSP13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DUSP13 purchase

MBS627164 is an antibody targeting DUSP13. Also known as DUSP13, NT (M1) (Dual Specificity Protein Phosphatase 13, Testis-and Skeletal-muscle-specific DSP, Dual Specificity Phosphatase SKRP4, TMDP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DUSP13. It may not necessarily be applicable to this product.

NCBI GI #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
DUSP13
UniProt Protein Name
Dual specificity protein phosphatase 13
UniProt Synonym Protein Names
Dual specificity phosphatase SKRP4; Testis- and skeletal-muscle-specific DSP
UniProt Gene Name
DUSP13
UniProt Synonym Gene Names
TMDP
UniProt Entry Name
DUS13_HUMAN

UniProt Comments for DUSP13

DUSP13: May be involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. Exhibits intrinsic phosphatase activity towards both phospho- seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 5 isoforms of the human protein are produced by alternative promoter.

Protein type: EC 3.1.3.16; EC 3.1.3.48; Cell cycle regulation; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity

Chromosomal Location of Human Ortholog: 10q22.2

Cellular Component: cytoplasm

Molecular Function: protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity

Biological Process: meiosis; spermatogenesis; protein amino acid dephosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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