Rabbit Anti-BGLF4 Polyclonal Antibody – Cat# MBS627290

Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human cancer tissue using MBS627290, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of MBS627290 for immunohistochemistry. BC = breast carcinoma; HC = hepatocarcinoma.

BGLF4 Antibody – Rabbit Polyclonal

Name: BGLF4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS627290
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS627290

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BGLF4, Polyclonal Antibody

Full Product Name

BGLF4, CT (Serine/Threonine-protein Kinase BGLF4)

Product Gene Name

anti-BGLF4 antibody

Product Synonym Names

Anti -BGLF4, CT (Serine/Threonine-protein Kinase BGLF4)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human BGLF4.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Chromosome Location

NC_007605.1 (108459..111326, complement)

3D Structure

ModBase 3D Structure for P0C731

Immunogen

Synthetic peptide selected from the C-terminal region of human BGLF4 (KLH).

Product Categories/Family for anti-BGLF4 antibody

Antibodies; Abs to Protein Kinases

Applications Tested/Suitable for anti-BGLF4 antibody

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-BGLF4 antibody

Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:50-1:100

Other Notes

Small volumes of anti-BGLF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BGLF4 purchase

MBS627290 is an antibody targeting BGLF4. Also known as BGLF4, CT (Serine/Threonine-protein Kinase BGLF4). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BGLF4. It may not necessarily be applicable to this product.

NCBI GI #

82503244

NCBI GeneID

3783704

UniProt Primary Accession #

P0C731

UniProt Related Accession #

P0C731

GenBank Nucleotide #

YP_401688.1

NCBI Official Full Name

BGLF4

NCBI Official Symbol

BGLF4

UniProt Protein Name

Serine/threonine-protein kinase BGLF4

Protein Family

Serine/threonine-protein kinase

UniProt Entry Name

KR2_EBVG

NCBI Protein Information

BGLF4; ORF36

UniProt Comments for BGLF4

Plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. Modifies the host nuclear envelope structure and induces the redistribution of nuclear envelope-associated proteins by phosphorylating host nucleoporins. Subsequently, promotes the nuclear transport of EBV lytic proteins. Required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. Contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. Induces disassembly of the nuclear lamina by phosphorylating with host LMNA. Phosphorylates substrates involved in capsid assembly and DNA packaging. Facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. Phosphorylates the viral immediate-early protein BZLF1 and inhibits its sumoylation by interacting with host SUMO1 and SUMO2.

Research Articles on BGLF4

1. Site-directed mutagenesis has been employed to generate mutations targeting residues involved in nuclear localization of the EBV-PK.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.