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NEK9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS628399

NEK9, a member of the NIMA subfamily of Ser/Thr protein kinases, is a pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. It phosphorylates different histones (serine and threonine residues… More details

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Product Overview

Online Datasheet in PDF
Product Name
NEK9, Polyclonal Antibody
Full Product Name
NEK9, CT (NIMA (Never in Mitosis Gene A)-Related Kinase 9, Never in Mitosis A-related Kinase 9, NIMA-related Kinase Nek9, NimA-related Protein Kinase 9, DKFZp434D0935, HGNC:18591, KIAA1995, MGC138306, MGC16714, Nercc1 Kinase, NERCC1, NERCC, NIMA-related K
Product Gene Name
anti-NEK9 antibody
Product Synonym Names
Anti -NEK9, CT (NIMA (Never in Mitosis Gene A)-Related Kinase 9, Never in Mitosis A-related Kinase 9, NIMA-related Kinase Nek9, NimA-related Protein Kinase 9, DKFZp434D0935, HGNC:18591, KIAA1995, MGC138306, MGC16714, Nercc1 Kinase, NERCC1, NERCC, NIMA-related K
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human NEK9. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
34,337 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (75548818..75593778, complement). Location: 14q24.3
3D Structure
ModBase 3D Structure for Q6PKF2
Immunogen
Synthetic peptide selected from the C-terminal region of human NEK9 (KLH).

Product Categories/Family for anti-NEK9 antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-NEK9 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NEK9 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-NEK9 antibody

The anti-NEK9 Pab is used in Western blot to detect NEK9 in 293 cell lysate (Lane 1) and mouse heart tissue lysate (Lane 2).
Rabbit Anti-NEK9 Polyclonal Antibody – Cat# MBS628399

Immunohistochemistry (IHC) of anti-NEK9 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-NEK9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS628399

Other Notes

Small volumes of anti-NEK9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NEK9 purchase

MBS628399 is an antibody targeting NEK9. Also known as NEK9, CT (NIMA (Never in Mitosis Gene A)-Related Kinase 9, Never in Mitosis A-related Kinase 9, NIMA-related Kinase Nek9, NimA-related Protein Kinase 9, DKFZp434D0935, HGNC:18591, KIAA1995, MGC138306, MGC16714, Nercc1 Kinase, NERCC1, NERCC, NIMA-related K. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NEK9. It may not necessarily be applicable to this product.

NCBI GI #
46255716
NCBI GeneID
91754
UniProt Primary Accession #
Q6PKF2
UniProt Related Accession #
Q6PKF2; Q8TD19
NCBI Official Full Name
NEK9 protein
NCBI Official Synonym Full Names
NIMA (never in mitosis gene a)- related kinase 9
NCBI Official Symbol
NEK9
NCBI Official Synonym Symbols
Nek8; NERCC; NERCC1; MGC16714; MGC138306; DKFZp434D0935
UniProt Protein Name
NEK9 protein
Protein Family
Serine/threonine-protein kinase
UniProt Gene Name
NEK9
UniProt Entry Name
Q6PKF2_HUMAN
NCBI Protein Information
serine/threonine-protein kinase Nek9; nercc1 kinase; nimA-related kinase 8; NIMA-related kinase Nek8; nimA-related protein kinase 9; never in mitosis A-related kinase 9

UniProt Comments for NEK9

NEK9: a protein kinase related to the NIMA (never in mitosis, gene A) serine/threonine kinase of Aspergillus nidulans. Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation.

Protein type: Autophagy; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; EC 2.7.11.1; Kinase, protein; Other group; NEK family

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: cytosol; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; metal ion binding; protein kinase binding; ATP binding

Biological Process: mitosis; cell division; mitotic nuclear envelope disassembly; mitotic cell cycle; protein amino acid phosphorylation
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Research Articles on NEK9

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NEK9 antibody

 Reference Product  PubMed Publications
 NEK6 antibody  >9 publications with NEK9 and NEK6
 NEK7 antibody  >8 publications with NEK9 and NEK7
 RAN antibody  >2 publications with NEK9 and RAN
 SUPT16H antibody  >1 publications with NEK9 and SUPT16H
 SSRP1 antibody  >1 publications with NEK9 and SSRP1
 BICD2 antibody  >1 publications with NEK9 and BICD2

Diseases associated with anti-NEK9 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with NEK9 and Neoplasms
 Kidney Diseases Antibodies  >2 publications with NEK9 and Kidney Diseases
 Breast Neoplasms Antibodies  >1 publications with NEK9 and Breast Neoplasms

Organs/Tissues associated with anti-NEK9 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with NEK9 and Kidney
 Lung Antibodies  >1 publications with NEK9 and Lung
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