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Cdc2l5 (CDK13) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS633608

The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Cdc2L5 (CDK13), Monoclonal Antibody
Full Product Name
Cdc2L5 (Cell Division Cycle 2-like 5, Cell Division Cycle 2-like Protein Kinase 5, CDC2-related Protein Kinase 5, CDC2L, CHED, Cholinesterase-related Cell Division Controller) (Azide Free)
Product Gene Name
anti-CDK13 antibody
Product Synonym Names
Anti -Cdc2L5 (Cell Division Cycle 2-like 5, Cell Division Cycle 2-like Protein Kinase 5, CDC2-related Protein Kinase 5, CDC2L, CHED, Cholinesterase-related Cell Division Controller) (Azide Free)
Clonality
Monoclonal
Isotype
IgG1k
Clone Number
10B2175
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human Cdc2L5.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
164,923 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (39989959..40136733). Location: 7p13
OMIM
603309
3D Structure
ModBase 3D Structure for Q14004
Immunogen
Full length recombinant protein corresponding to aa1-325 of human CDC2L5 (AAH01274) with GST tag. MW of GST tag alone is 26kD.
Hybridoma
Sp2/0 myeloma cells with spleen cells from Balb/c mice.

Product Categories/Family for anti-CDK13 antibody

Antibodies; Abs to Cell Division Cycle (CDC)
Applications Tested/Suitable for anti-CDK13 antibody
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-CDK13 antibody
Suitable for use in ELISA, Immunofluorescence and Western Blot.
Dilution: Western Blot: 1:500-1:1000
ELISA: 3ng/ml-1ug/ml

ELISA (EIA) of anti-CDK13 antibody

Sandwich ELISA analysis: Detection limit of MBS633608 is 0.1ng/ml as capture antibody
Mouse Anti-CDK13 Monoclonal Antibody – Cat# MBS633608

Western Blot (WB) of anti-CDK13 antibody

Western Blot analysis of expression in Hela S3 NE using C2579-51Y
Mouse Anti-CDK13 Monoclonal Antibody, Western Blot (WB) – Cat# MBS633608

Immunofluorescence (IF) of anti-CDK13 antibody

Immunofluorescence analysis of HeLa cell using MBS633608 (10ug/ml)
Mouse Anti-CDK13 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS633608

Other Notes

Small volumes of anti-CDK13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK13 purchase

MBS633608 is an antibody targeting CDK13. Also known as Cdc2L5 (Cell Division Cycle 2-like 5, Cell Division Cycle 2-like Protein Kinase 5, CDC2-related Protein Kinase 5, CDC2L, CHED, Cholinesterase-related Cell Division Controller) (Azide Free). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK13. It may not necessarily be applicable to this product.

NCBI GI #
145309302
NCBI GeneID
8621
NCBI Accession #
NP_003709.3
UniProt Primary Accession #
Q14004
UniProt Secondary Accession #
Q53G78; Q6DKQ9; Q75MH4; Q75MH5; Q96JN4; Q9H4A0; Q9H4A1; Q9UDR4
UniProt Related Accession #
Q14004
GenBank Nucleotide #
NM_003718.4
NCBI Official Full Name
cyclin-dependent kinase 13 isoform 1
NCBI Official Synonym Full Names
cyclin-dependent kinase 13
NCBI Official Symbol
CDK13
NCBI Official Synonym Symbols
CHED; CDC2L; CDC2L5; hCDK13
UniProt Protein Name
Cyclin-dependent kinase 13
UniProt Synonym Protein Names
CDC2-related protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; hCDK13; Cholinesterase-related cell division controller
Protein Family
Cyclin-dependent kinase
UniProt Gene Name
CDK13
UniProt Synonym Gene Names
CDC2L; CDC2L5; CHED; KIAA1791; hCDK13
UniProt Entry Name
CDK13_HUMAN
NCBI Protein Information
cyclin-dependent kinase 13; CDC2-related protein kinase 5; cell division protein kinase 13; cell division cycle 2-like protein kinase 5; cholinesterase-related cell division controller

UniProt Comments for CDK13

CDK13: a CMGC protein kinase of the CDK family. It has been reported to interact with L-type cyclins. Overexpression of CDC2L5 constructs disturbs constitutive splicing and switches alternative splice site selection in vivo suggesting that it may regulate alternative splicing. It has unusually large N- and C-termini and is ubiquitously expressed in many tissues. Two alternatively spliced human isoforms have been described.

Protein type: RNA splicing; EC 2.7.11.22; Protein kinase, CMGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.23; Motility/polarity/chemotaxis; Cell cycle regulation; CMGC group; CDK family; CRK7 subfamily; CDK/CRK7 subfamily

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleoplasm; Golgi apparatus; extracellular space; nuclear cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nuclear speck

Molecular Function: RNA polymerase subunit kinase activity; cyclin binding; protein binding; cyclin-dependent protein kinase activity; ATP binding; protein kinase activity

Biological Process: alternative nuclear mRNA splicing, via spliceosome; viral reproduction; multicellular organismal development; positive regulation of cell proliferation; regulation of mitosis; hemopoiesis
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Research Articles on CDK13

1. Coincidently amplified CDK13, GMNN, and CENPF genes can play a role as common cancer-driver genes in human cancers.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CDK13 antibody

 Reference Product  PubMed Publications
 CDK12 antibody  >5 publications with CDK13 and CDK12

Diseases associated with anti-CDK13 antibody

 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >1 publications with CDK13 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with CDK13 and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with CDK13 and Liver Diseases
 Adenocarcinoma Antibodies  >1 publications with CDK13 and Adenocarcinoma
 Neoplasms Antibodies  >1 publications with CDK13 and Neoplasms

Organs/Tissues associated with anti-CDK13 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >1 publications with CDK13 and Bone Marrow
 Bone Antibodies  >1 publications with CDK13 and Bone
 Heart Antibodies  >1 publications with CDK13 and Heart
 Blood Antibodies  >1 publications with CDK13 and Blood
 Liver Antibodies  >1 publications with CDK13 and Liver
 Lung Antibodies  >1 publications with CDK13 and Lung
 Embryonic Tissue Antibodies  >1 publications with CDK13 and Embryonic Tissue
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