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U73122 1-(6-(17 beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione Reagent – Molecular Biology

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635346

U73122 inhibits agonist induced phospholipase C (PLC) activation in human platelets and neutrophils. This compound also inhibits agonist-induced down-regulation of muscarinic receptors in SK-N-SH neuroblastoma cells. U73122 is a useful tool for investigating More details

$670 / 5 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
U73122 1-(6-(17 beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione, Reagent
Full Product Name
U73122 1-(6-(17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione
Product Synonym Names
U73122 1-(6-(17 -3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione
Form/Format
Off-white, lyophilized powder
Purity/Purification
Highly Purified
~98% (TLC)
Preparation and Storage
Store, as supplied, at room temperature. Upon solubilization, apportion into working aliquots and store at -20 degree C. Avoid repeated freeze/thaw cycles. Solutions are stable at -20 degree C for up to two months. Discard solutions that have turned a pink color, as this indicates a loss in inhibitory activity.
Molecular Weight
464.7
CAS Number
112648-68-7
Biological Activity
IC50 = 1.0-2.1uM (agonist induced PLC activation in human platelets and neutrophils)
Molecular Formula
C29H40N2O3
Solubility
Soluble in chloroform; soluble in methylene chloride; soluble in DMSO at a concentration of 2mg/ml; and soluble in ethanol at a concentration of 1mg/ml.

Other Notes

Small volumes of U73122 1-(6-(17 beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione reagent vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for U73122 1-(6-(17 beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione purchase

MBS635346 is a reagent targeting U73122 1-(6-(17 beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione. Also known as U73122 1-(6-(17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione.
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