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Cyclophilin D (PPIF) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS635492

Cyclophilin D (also known as peptidylpropyl isomerase D, PPID) is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cyclophilin D (Ppif), Recombinant Protein
Full Product Name
Cyclophilin D, Recombinant, Human (PPID, Peptidylprolyl Isomerase D, 40kD Peptidyl-Prolyl cis-trans isomeras, Cyclophilin-40, Cyclophilin-Related Protein, CYP40, CYP-40, CYPD, MGC33096, PPIase, Rotamase)
Product Gene Name
Sequence
MGSSHHHHHH SSGLVPRGSH MSHPSPQAKP SNPSNPRVFF DVDIGGERVG RIVLELFADI VPKTAENFRA LCTGEKGIGH TTGKPLHFKG CPFHRIIKKF MIQGGDFSNQ NGTGGESIYG EKFEDENFHY KHDREGLLSM ANAGRNTNGS QFFITTVPTP HLDGKHVVFG QVIKGIGVAR ILENVEVKGE KPAKLCVIAE CGELKEGDDG GIFPKDGSGD SHPDFPEDAD IDLKDVDKIL LITEDLKNIG NTFFKSQNWE MAIKKYAEVL RYVDSSKAVI ETADRAKLQP IALSCVLNIG ACKLKMSNWQ GAIDSCLEAL ELDPSNTKAL YRRAQGWQGL KEYDQALADL KKAQGIAPED KAIQAELLKV KQKIKAQKDK EKAVYAKMFA
Form/Format
Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Purity/Purification
>95%
Concentration
1mg/ml (lot specific)
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
42.9kD
Chromosome Location
Chromosome: 16; NC_005115.3 (1955730..1962451). Location: 16p16
3D Structure
ModBase 3D Structure for P29117
Source
E coli
Applications Tested/Suitable for Ppif recombinant protein
Western Blot. Other applications not tested.
Application Notes for Ppif recombinant protein
Suitable for use in Western Blot.

SDS-Page of Ppif recombinant protein

15% SDS-PAGE using C8855-21 (3ug)
PPIF Recombinant Protein – Cat# MBS635492

Other Notes

Small volumes of Ppif recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ppif purchase

MBS635492 is a recombinant protein targeting Ppif. Also known as Cyclophilin D, Recombinant, Human (PPID, Peptidylprolyl Isomerase D, 40kD Peptidyl-Prolyl cis-trans isomeras, Cyclophilin-40, Cyclophilin-Related Protein, CYP40, CYP-40, CYPD, MGC33096, PPIase, Rotamase).

Additional Details

NCBI/Uniprot data below describe general gene information for Ppif. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
cyclophilin D
NCBI Official Synonym Full Names
peptidylprolyl isomerase F
NCBI Official Symbol
Ppif
NCBI Official Synonym Symbols
CypD; CyP-D; PPIase
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase F, mitochondrial
UniProt Synonym Protein Names
Cyclophilin D; CyP-D; CypD; Cyclophilin F; Rotamase F
UniProt Gene Name
Ppif
UniProt Synonym Gene Names
PPIase F; CyP-D; CypD
UniProt Entry Name
PPIF_RAT
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase F, mitochondrial; PPIase F; rotamase F; cyclophilin D; cyclophilin F

NCBI Summary for Ppif

mitochondrial isozyme of peptidyl-prolyl cis-trans-isomerase; enzyme activity is inhibited by cyclosporin A [RGD, Feb 2006]

UniProt Comments for Ppif

PPIF: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family.

Protein type: Cyclophilin; Apoptosis; Mitochondrial; Isomerase; EC 5.2.1.8

Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex

Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity; peptide binding; cyclosporin A binding

Biological Process: regulation of apoptosis; apoptotic mitochondrial changes; protein peptidyl-prolyl isomerization; protein folding; regulation of mitochondrial membrane permeability; response to oxidative stress; negative regulation of ATPase activity; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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