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Leptin, Triple Antagonist Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS637070

Leptin Antagonist Triple Mutant Human Recombinant is a single non-glycosilated polypeptide chain containing 146 amino and additional Ala at N-terminus acids and having a molecular weight of 16kD. Leptin was mutated, resulting in L39A/D40A/F41A. Leptin… More details

$460 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Leptin, Triple Antagonist, Active Protein
Full Product Name
Leptin, Triple Antagonist (tA), Recombinant, Human (LEP, Leptin Mouse Obesity Homolog, Leptin Precursor Obesity Factor, Ob, Obese Protein, Obesity, Obesity Factor, Obesity Homolog Mouse, OBS)
Species Reactivity
Human
Form/Format
Supplied as lyophilized powder from a concentrated 1mg/ml solution with NaHCO3.
Purity/Purification
Highly Purified
98.0% as determined by RP-HPLC or SDS-PAGE.
Preparation and Storage
Lyophilized Leptin protein although stable at room temperature for 3 weeks, should be stored desiccated below -20 degree C. Upon reconstitution IL6 should be stored at 4 degree C between 2-7 days and for future use below -20 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
Molecular Weight
16kD
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Leptin triple antagonist is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. It also inhibits various leptin effects in several in vitro bioassays.
Protein Content
Protein quantitation was carried out by UV spectroscopy at 280 nm using the absorbency value of 0.88 as the extinction coefficient for a 0.1% (1mg/ml) solution at pH 8.0. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).

Product Categories/Family for Leptin, Triple Antagonist active protein

Molecular Biology; MB-Obesity

Other Notes

Small volumes of Leptin, Triple Antagonist active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Leptin, Triple Antagonist purchase

MBS637070 is an active protein targeting Leptin, Triple Antagonist. Also known as Leptin, Triple Antagonist (tA), Recombinant, Human (LEP, Leptin Mouse Obesity Homolog, Leptin Precursor Obesity Factor, Ob, Obese Protein, Obesity, Obesity Factor, Obesity Homolog Mouse, OBS). Reactive in Human.
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