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IFNA17 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6382260

MaxLight405 is a new Violet photostable dye conjugate comparable to Alexa Fluor 405, PacificBlue, Brilliant Violet 421 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (400nm); Emission (423nm); Extinction… More details

$965 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IFNA17, Polyclonal Antibody
Full Product Name
IFNA17 (Interferon alpha-17, IFN-alpha-17, Interferon alpha-88, LeIF I, Interferon alpha-T, Interferon alpha-I') (MaxLight 405)
Product Gene Name
anti-IFNA17 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human IFNA17.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
21,728 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (21227242..21228221, complement). Location: 9p22
OMIM
147583
3D Structure
ModBase 3D Structure for P01571
Immunogen
Full length aa1-189 corresponding to human IFNA17.
Immunogen Sequence
MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFGLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKILRRKD
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-IFNA17 antibody

Antibodies; Interferon
Applications Tested/Suitable for anti-IFNA17 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes for anti-IFNA17 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-IFNA17 antibody

Western Blot analysis of IFNA17 expression in transfected 293T cell line usingMBS6012689. Lane 1: IFNA17 transfected lysate (21.7kD). Lane 2: Non-transfected lysate.
Rabbit Anti-IFNA17 Polyclonal Antibody – Cat# MBS6382260

Western Blot (WB) of anti-IFNA17 antibody

Western Blot analysis of IFNA17 expression in rat brain usingMBS6012689.
Rabbit Anti-IFNA17 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6382260

Immunofluorescence (IF) of anti-IFNA17 antibody

Immunofluorescence of IFNA17 on HeLa cell using MBS6012689 (30ug/ml).
Rabbit Anti-IFNA17 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6382260

Other Notes

Small volumes of anti-IFNA17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IFNA17 purchase

MBS6382260 is an antibody targeting IFNA17. Also known as IFNA17 (Interferon alpha-17, IFN-alpha-17, Interferon alpha-88, LeIF I, Interferon alpha-T, Interferon alpha-I') (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IFNA17. It may not necessarily be applicable to this product.

NCBI GI #
10880985
NCBI GeneID
3451
NCBI Accession #
NP_067091.1
UniProt Primary Accession #
P01571
UniProt Secondary Accession #
Q14639; Q4KMT4; Q5VZ53; Q7M4Q4
UniProt Related Accession #
P01571
GenBank Nucleotide #
NM_021268
NCBI Official Full Name
interferon alpha-17
NCBI Official Synonym Full Names
interferon, alpha 17
NCBI Official Symbol
IFNA17
NCBI Official Synonym Symbols
IFNA; INFA; LEIF2C1; IFN-alphaI
UniProt Protein Name
Interferon alpha-17
UniProt Synonym Protein Names
Interferon alpha-88; Interferon alpha-I'; LeIF I; Interferon alpha-T
Protein Family
Interferon
UniProt Gene Name
IFNA17
UniProt Synonym Gene Names
IFN-alpha-17; LeIF I
UniProt Entry Name
IFN17_HUMAN
NCBI Protein Information
interferon alpha-17; leIF I; IFN-alpha-17; interferon alpha-T; interferon alpha-88; interferon alpha-I'; interferon alpha-WA

UniProt Comments for IFNA17

IFNA17: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family.

Protein type: Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular space; extracellular region

Molecular Function: interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; response to exogenous dsRNA; response to virus; B cell differentiation; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; natural killer cell activation during immune response; innate immune response; blood coagulation; defense response to virus; humoral immune response; T cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein
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Research Articles on IFNA17

1. We did not reproduce the associations previously noted with the TNF, IFNA10, IFNA17, and IFNG genes with pulmonary sarcoidosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFNA17 antibody

 Reference Product  PubMed Publications
 STAT1 antibody  >683 publications with IFNA17 and STAT1
 IFNAR1 antibody  >334 publications with IFNA17 and IFNAR1
 IFNAR2 antibody  >178 publications with IFNA17 and IFNAR2
 TLR3 antibody  >148 publications with IFNA17 and TLR3
 MYD88 antibody  >125 publications with IFNA17 and MYD88
 IRF7 antibody  >122 publications with IFNA17 and IRF7
 IRF1 antibody  >116 publications with IFNA17 and IRF1
 IRF2 antibody  >43 publications with IFNA17 and IRF2
 HLA-B antibody  >32 publications with IFNA17 and HLA-B
 IRF5 antibody  >31 publications with IFNA17 and IRF5

Pathways associated with anti-IFNA17 antibody

 Products by Pathway  Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Hepatitis B Pathway antibodies  Hepatitis B Pathway Diagram

Diseases associated with anti-IFNA17 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >11450 publications with IFNA17 and Liver Diseases
 Neoplasms Antibodies  >9857 publications with IFNA17 and Neoplasms
 Hepatitis C Antibodies  >9714 publications with IFNA17 and Hepatitis C
 Cardiovascular Diseases Antibodies  >1455 publications with IFNA17 and Cardiovascular Diseases
 HIV Infections Antibodies  >1428 publications with IFNA17 and HIV Infections
 Nervous System Diseases Antibodies  >1408 publications with IFNA17 and Nervous System Diseases
 Inflammation Antibodies  >1387 publications with IFNA17 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >1095 publications with IFNA17 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1058 publications with IFNA17 and Liver Neoplasms
 Anemia Antibodies  >812 publications with IFNA17 and Anemia
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