Mouse Anti-GNA15 Polyclonal Antibody – Cat# MBS641334

Western Blot analysis of GNA15 expression in transfected 293T cell line by GNA15 polyclonal antibody. Lane 1: GNA15 transfected lysate (41.25kD). Lane 2: Non-transfected lysate.

GNA15 Antibody – Mouse Polyclonal

Name: GNA15 Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS641334
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641334

Ga16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. The G protein is known to couple a large number of G protein-coupled receptors… More details

$880 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GNA15, Polyclonal Antibody

Full Product Name

GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)

Product Gene Name

anti-GNA15 antibody

Product Synonym Names

Anti -GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)

Immunogen Sequence

MARSLTWRCC PWCLTEDEKA AARVDQEINR ILLEQKKQDR GELKLLLLGP GESGKSTFIK QMRIIHGAGY SEEERKGFRP LVYQNIFVSM RAMIEAMERL QIPFSRPESK HHASLVMSQD PYKVTTFEKR YAAAMQWLWR DAGIRACYER RREFHLLDSA VYYLSHLERI TEEGYVPTAQ DVLRSRMPTT GINEYCFSVQ KTNLRIVDVG GQKSERKKWI HCFENVIALI YLASLSEYDQ CLEENNQENR MKESLALFGT ILELPWFKST SVILFLNKTD ILEEKIPTSH LATYFPSFQG PKQDAEAAKR FILDMYTRMY TGCVDGPEGS KKGARSRRLF SHYTCATDTQ NIRKVFKDVR DSVLARYLDE INLL

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human GNA15.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

43,568 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (3136191..3163766). Location: 19p13.3

OMIM

139314

3D Structure

ModBase 3D Structure for P30679

Immunogen

Full length human GNA15, aa1-374 (AAH13585.1).

Product Categories/Family for anti-GNA15 antibody

Antibodies; Abs to G Proteins

Applications Tested/Suitable for anti-GNA15 antibody

Western Blot (WB)

Application Notes for anti-GNA15 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-GNA15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNA15 purchase

MBS641334 is an antibody targeting GNA15. Also known as GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GNA15. It may not necessarily be applicable to this product.

NCBI GI #

156104883

NCBI GeneID

2769

NCBI Accession #

NP_002059.2

UniProt Primary Accession #

P30679

UniProt Secondary Accession #

O75247; Q53XK2; E9KL40; E9KL47

UniProt Related Accession #

P30679

GenBank Nucleotide #

NM_002068.2

NCBI Official Full Name

guanine nucleotide-binding protein subunit alpha-15

NCBI Official Synonym Full Names

guanine nucleotide binding protein (G protein), alpha 15 (Gq class)

NCBI Official Symbol

GNA15

NCBI Official Synonym Symbols

GNA16

UniProt Protein Name

Guanine nucleotide-binding protein subunit alpha-15

UniProt Synonym Protein Names

Epididymis tissue protein Li 17E; Guanine nucleotide-binding protein subunit alpha-16

Protein Family

Guanine nucleotide-binding protein

UniProt Gene Name

GNA15

UniProt Synonym Gene Names

GNA16; G alpha-15; G-protein subunit alpha-15; G alpha-16

UniProt Entry Name

GNA15_HUMAN

NCBI Protein Information

guanine nucleotide-binding protein subunit alpha-15; g alpha-15; g alpha-16; G-protein subunit alpha-15; G-protein subunit alpha-16; epididymis tissue protein Li 17E; guanine nucleotide-binding protein subunit alpha-16

UniProt Comments for GNA15

G-alpha 15: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Belongs to the G-alpha family. G(q) subfamily.

Protein type: G protein; G protein, heterotrimeric alpha G(q); G protein, heterotrimeric

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: plasma membrane; heterotrimeric G-protein complex

Molecular Function: GTPase activity; signal transducer activity; GTP binding; G-protein-coupled receptor binding; metal ion binding; G-protein beta/gamma-subunit binding

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; platelet activation; elevation of cytosolic calcium ion concentration; phospholipase C activation; metabolic process; dopamine receptor, phospholipase C activating pathway; blood coagulation; muscarinic acetylcholine receptor, phospholipase C activating pathway

Research Articles on GNA15

1. G15 ectopic presence could functionally contribute to the transformation process since siRNA-induced depletion of Galpha15 in pancreatic carcinoma cell lines dramatically inhibited anchorage-independent growth and resistance to the lack of nutrients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GNA15 antibody

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ADP Signalling Through P2Y Purinoceptor 1 Pathway antibodies	ADP Signalling Through P2Y Purinoceptor 1 Pathway Diagram
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Arf6 Signaling Events Pathway antibodies	Arf6 Signaling Events Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Endothelin Pathway antibodies	Endothelin Pathway Diagram
G Protein Signaling Pathways antibodies	G Protein Signaling Pathways Diagram

Diseases associated with anti-GNA15 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with GNA15 and Neoplasms

Organs/Tissues associated with anti-GNA15 antibody

Organ/Tissue Name	Pubmed Publications
Uterus Antibodies	>1 publications with GNA15 and Uterus
Kidney Antibodies	>1 publications with GNA15 and Kidney
Spleen Antibodies	>1 publications with GNA15 and Spleen
Bone Marrow Antibodies	>1 publications with GNA15 and Bone Marrow
Liver Antibodies	>1 publications with GNA15 and Liver
Brain Antibodies	>1 publications with GNA15 and Brain
Lung Antibodies	>1 publications with GNA15 and Lung