Mouse Anti-TGS1 Monoclonal Antibody – Cat# MBS642074

Detection limit for recombinant GST tagged NCOA6IP is ~0.3ng/ml as a capture antibody.

PIPMT (TGS1) Antibody – Mouse Monoclonal

Name: TGS1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS642074
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642074

The nuclear receptor coactivators participate in the transcriptional activation of specific genes by nuclear receptors. Using a coactivator peroxisome proliferator-activated receptor-interacting protein (PRIP) as bait, a novel, protein has been identified,… More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PIPMT (TGS1), Monoclonal Antibody

Full Product Name

PIPMT (Cap-specific Guanine-N2 Methyltransferase, Nuclear Receptor Coactivator 6-interacting Protein, PRIP-interacting Protein With Methyltransferase Motif, PIMT, Trimethylguanosine Synthase, CLL-associated Antigen KW-2, Hepatocellular Carcinoma-associate

Product Gene Name

anti-TGS1 antibody

Product Synonym Names

Anti -PIPMT (Cap-specific Guanine-N2 Methyltransferase, Nuclear Receptor Coactivator 6-interacting Protein, PRIP-interacting Protein With Methyltransferase Motif, PIMT, Trimethylguanosine Synthase, CLL-associated Antigen KW-2, Hepatocellular Carcinoma-associate

Immunogen Sequence

MRVIAIDIDP VKIALARNNA EVYGIADKIE FICGDFLLLA SFLKADVVFL SPPWGGPDYA TAETFDIRTM MSPDGFEIFR LSKKITNNIV YFLPRNADID QVASLAGPGG QVEIEQNFLN NKLKTITAYF GDLIRRPASE T

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

3F1

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human NCOA6IP.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

96,620 Da

Chromosome Location

Chromosome: 8; NC_000008.10 (56685791..56738007). Location: 8q11

OMIM

606461

3D Structure

ModBase 3D Structure for Q96RS0

Immunogen

Full length recombinant corresponding to aa1-142 from human NCOA6IP (AAH11999) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-TGS1 antibody

Antibodies; Abs to Transcription Factors

Applications Tested/Suitable for anti-TGS1 antibody

ELISA (EL/EIA)

Application Notes for anti-TGS1 antibody

Suitable for use in ELISA.

Other Notes

Small volumes of anti-TGS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TGS1 purchase

MBS642074 is an antibody targeting TGS1. Also known as PIPMT (Cap-specific Guanine-N2 Methyltransferase, Nuclear Receptor Coactivator 6-interacting Protein, PRIP-interacting Protein With Methyltransferase Motif, PIMT, Trimethylguanosine Synthase, CLL-associated Antigen KW-2, Hepatocellular Carcinoma-associate. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TGS1. It may not necessarily be applicable to this product.

NCBI GI #

530388618

NCBI GeneID

96764

NCBI Accession #

XP_005251385.1

UniProt Primary Accession #

Q96RS0

UniProt Secondary Accession #

Q5GH23; Q8TDG9; Q96QU3; Q9H5V3; A6NJQ5

UniProt Related Accession #

Q96RS0

GenBank Nucleotide #

XM_005251328.1

NCBI Official Full Name

trimethylguanosine synthase isoform X1

NCBI Official Synonym Full Names

trimethylguanosine synthase 1

NCBI Official Symbol

TGS1

NCBI Official Synonym Symbols

PIMT; PIPMT; NCOA6IP

UniProt Protein Name

Trimethylguanosine synthase

UniProt Synonym Protein Names

CLL-associated antigen KW-2; Cap-specific guanine-N2 methyltransferase; Hepatocellular carcinoma-associated antigen 137; Nuclear receptor coactivator 6-interacting protein; PRIP-interacting protein with methyltransferase motif

Protein Family

Probable diacyglycerol O-acyltransferase

UniProt Gene Name

TGS1

UniProt Synonym Gene Names

HCA137; NCOA6IP; PIMT; PIMT; PIPMT

UniProt Entry Name

TGS1_HUMAN

NCBI Protein Information

trimethylguanosine synthase; SEREX-defined; CLL-associated antigen KW-2; PRIP-interacting protein PIPMT; trimethylguanosine synthase homolog; cap-specific guanine-N2 methyltransferase; hepatocellular carcinoma-associated antigen 137; nuclear receptor coactivator 6 interacting protein; nuclear receptor coactivator 6-interacting protein; PRIP-interacting protein with methyltransferase motif; PRIP-interacting protein with methyltransferase domain

UniProt Comments for TGS1

PIMT: a nuclear protein and apparent methyltransferase. Binds S-adenosyl-L-methionine and RNA. Plays a role in transcriptional regulation. Interacts with NCOA, CBP, p300, and PPARBP. Ubiquitously expressed. High expression in heart, skeletal muscle, kidney, liver and placenta.

Protein type: Methyltransferase; Nuclear receptor co-regulator; EC 2.1.1.-; RNA processing

Chromosomal Location of Human Ortholog: 8q11

Cellular Component: small nuclear ribonucleoprotein complex; nucleoplasm; Cajal body; extracellular space; cytoplasm; nucleus; cytosol

Molecular Function: protein binding

Biological Process: spliceosomal snRNP biogenesis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; ribonucleoprotein complex biogenesis and assembly; RNA capping; gene expression; cellular lipid metabolic process

Research Articles on TGS1

1. isoforms of the PIMT/Tgs1 protein with an RNA methyltransferase domain function both in the nucleus and in the cytoplasm

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TGS1 antibody

Reference Product	PubMed Publications
NCOA6 antibody	>1 publications with TGS1 and NCOA6

Pathways associated with anti-TGS1 antibody

Products by Pathway	Pathway Diagram
Activation Of Gene Expression By SREBP (SREBF) Pathway antibodies	Activation Of Gene Expression By SREBP (SREBF) Pathway Diagram
BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway antibodies	BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway Diagram
Circadian Clock Pathway antibodies	Circadian Clock Pathway Diagram
Circadian Repression Of Expression By REV-ERBA Pathway antibodies	Circadian Repression Of Expression By REV-ERBA Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram

Diseases associated with anti-TGS1 antibody

Disease Name	Pubmed Publications
Anemia Antibodies	>1 publications with TGS1 and Anemia

Organs/Tissues associated with anti-TGS1 antibody

Organ/Tissue Name	Pubmed Publications
Uterus Antibodies	>1 publications with TGS1 and Uterus
Testis Antibodies	>1 publications with TGS1 and Testis
Blood Antibodies	>1 publications with TGS1 and Blood
Brain Antibodies	>1 publications with TGS1 and Brain