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SCARA5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642871

Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by… More details

$935 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SCARA5, Polyclonal Antibody
Full Product Name
SCARA5, CT (Scavenger Receptor Class A Member 5, Scavenger Receptor Hlg, UNQ2938/PRO28700)
Product Gene Name
anti-SCARA5 antibody
Product Synonym Names
Anti -SCARA5, CT (Scavenger Receptor Class A Member 5, Scavenger Receptor Hlg, UNQ2938/PRO28700)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SCARA5. Species sequence homology: Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
53,994 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (27727399..27850369, complement). Location: 8p21.1
OMIM
611306
3D Structure
ModBase 3D Structure for Q6ZMJ2
Immunogen
Synthetic peptide corresponding to SCARA5 at C-terminal conjugated to KLH.

Product Categories/Family for anti-SCARA5 antibody

Antibodies; Abs to Receptors; Scavenger
Applications Tested/Suitable for anti-SCARA5 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes for anti-SCARA5 antibody
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Dilution: Western Blot: 1-2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-SCARA5 antibody

Human Small Intestine: Formalin- Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-SCARA5 Polyclonal Antibody – Cat# MBS642871

Western Blot (WB) of anti-SCARA5 antibody

Western blot analysis of SCARA5 in human liver tissue lysate with SCARA5 antibody at 1ug/ml.
Rabbit Anti-SCARA5 Polyclonal Antibody, Western Blot (WB) – Cat# MBS642871

Other Notes

Small volumes of anti-SCARA5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCARA5 purchase

MBS642871 is an antibody targeting SCARA5. Also known as SCARA5, CT (Scavenger Receptor Class A Member 5, Scavenger Receptor Hlg, UNQ2938/PRO28700). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SCARA5. It may not necessarily be applicable to this product.

NCBI GI #
47271477
NCBI GeneID
286133
NCBI Accession #
NP_776194.2
UniProt Primary Accession #
Q6ZMJ2
UniProt Secondary Accession #
Q6UXZ1; Q7Z4A1; Q8N4Z7
UniProt Related Accession #
Q6ZMJ2
GenBank Nucleotide #
NM_173833.5
NCBI Official Full Name
scavenger receptor class A member 5
NCBI Official Synonym Full Names
scavenger receptor class A, member 5 (putative)
NCBI Official Symbol
SCARA5
NCBI Official Synonym Symbols
Tesr; NET33
UniProt Protein Name
Scavenger receptor class A member 5
UniProt Synonym Protein Names
Scavenger receptor hlg
Protein Family
Scavenger receptor
UniProt Gene Name
SCARA5
UniProt Entry Name
SCAR5_HUMAN
NCBI Protein Information
scavenger receptor class A member 5; scavenger receptor hlg; testis expressed scavenger receptor

UniProt Comments for SCARA5

SCARA5: Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). Belongs to the SCARA5 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p21.1

Cellular Component: cell surface; integral to plasma membrane

Molecular Function: scavenger receptor activity

Biological Process: receptor-mediated endocytosis; regulation of gene expression; cellular iron ion homeostasis; regulation of blood coagulation; endocytosis
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Research Articles on SCARA5

1. Results demonstrate the involvement of SCARA3 and SCARA5 in the uptake of PF14-oligonucleotide nanocomplexes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SCARA5 antibody

 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging By Class A Receptors Pathway antibodies  Scavenging By Class A Receptors Pathway Diagram

Diseases associated with anti-SCARA5 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with SCARA5 and Neoplasms
 Carcinoma Antibodies  >5 publications with SCARA5 and Carcinoma
 Liver Diseases Antibodies  >5 publications with SCARA5 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with SCARA5 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >3 publications with SCARA5 and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >3 publications with SCARA5 and Cardiovascular Diseases
 Inflammation Antibodies  >2 publications with SCARA5 and Inflammation
 Adenocarcinoma Antibodies  >2 publications with SCARA5 and Adenocarcinoma
 Lung Neoplasms Antibodies  >2 publications with SCARA5 and Lung Neoplasms
 Liver Cirrhosis Antibodies  >1 publications with SCARA5 and Liver Cirrhosis

Organs/Tissues associated with anti-SCARA5 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with SCARA5 and Liver
 Lung Antibodies  >3 publications with SCARA5 and Lung
 Kidney Antibodies  >2 publications with SCARA5 and Kidney
 Uterus Antibodies  >2 publications with SCARA5 and Uterus
 Testis Antibodies  >2 publications with SCARA5 and Testis
 Embryonic Tissue Antibodies  >1 publications with SCARA5 and Embryonic Tissue
 Ovary Antibodies  >1 publications with SCARA5 and Ovary
 Placenta Antibodies  >1 publications with SCARA5 and Placenta
 Connective Tissue Antibodies  >1 publications with SCARA5 and Connective Tissue
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