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TIMP-4 (TIMP4) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643795

The matrix metalloproteinases (MMPs) are a large family of zinc endopeptidases that degrade extracellular matrix components such as fibronectin and collagen type III. The tissue inhibitors of metalloproteinase (TIMPs) complex with these matrix… More details

$785 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TIMP-4 (TIMP4), Polyclonal Antibody
Full Product Name
TIMP-4, CT (TIMP4, Tissue Inhibitor of Metalloproteinases 4)
Product Gene Name
Product Synonym Names
Anti -TIMP-4, CT (TIMP4, Tissue Inhibitor of Metalloproteinases 4)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human TIMP4. Species Crossreactivity: Mouse, rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,593 Da
Chromosome Location
Chromosome: 22; AC_000179.1 (57602210..57609085). Location: chromosome: 22
3D Structure
ModBase 3D Structure for O97563
Immunogen
Synthetic peptide corresponding to human TIMP4 at C-Terminal.
Applications Tested/Suitable for anti-TIMP4 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TIMP4 antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 5ug/ml

Immunohistochemistry (IHC) of anti-TIMP4 antibody

TIMP4 (5ug/ml) was used in IHC to stain ormalin-fixed, paraffin-embedded human uterus, endometrium, followed by biotinylated goat,r abbit IgG, alkaline phosphatase-streptavidin and chromogen.
Rabbit Anti-TIMP4 Polyclonal Antibody – Cat# MBS643795

Western Blot (WB) of anti-TIMP4 antibody

Western blot analysis of extracts from NIH-3T3 cells, using TIMP4. The lane on the right is treated with the synthesized peptide
Rabbit Anti-TIMP4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS643795

Other Notes

Small volumes of anti-TIMP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TIMP4 purchase

MBS643795 is an antibody targeting TIMP4. Also known as TIMP-4, CT (TIMP4, Tissue Inhibitor of Metalloproteinases 4). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TIMP4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
TPA: metalloproteinase inhibitor 4
NCBI Official Synonym Full Names
TIMP metallopeptidase inhibitor 4
NCBI Official Symbol
TIMP4
UniProt Protein Name
Metalloproteinase inhibitor 4
UniProt Synonym Protein Names
Tissue inhibitor of metalloproteinases 4
UniProt Gene Name
TIMP4
UniProt Synonym Gene Names
TIMP-4
UniProt Entry Name
TIMP4_BOVIN
NCBI Protein Information
metalloproteinase inhibitor 4; TIMP-4; tissue inhibitor of metalloproteinase; tissue inhibitor of metalloproteinases 4

UniProt Comments for TIMP4

Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the protease inhibitor I35 (TIMP) family. [View classification]Contains 1 NTR domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TIMP4 antibody

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