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HSPA4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644138

HSPA4 was originally suggested to be a member of the heat shock protein 70 family. However it is now known that human HSPA4 is a equivalent to mouse the Apg-2 protein and is a member of the Hsp110 family. More details

$970 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HSPA4, Polyclonal Antibody
Full Product Name
HSPA4 (Heat Shock 70kD Protein 4, Heat Shock 70-related Protein APG-2, HSP70RY, APG2)
Product Gene Name
anti-HSPA4 antibody
Product Synonym Names
Anti -HSPA4 (Heat Shock 70kD Protein 4, Heat Shock 70-related Protein APG-2, HSP70RY, APG2)
Immunogen Sequence
MSVVGIDLGF QSCYVAVARA GGIETIANEY SDRCTPACIS FGPKNRSIGA AAKSQVISNA KNTVQGFKRF HGRAFSDPFV EAEKSNLAYD IVQLPTGLTG IKVTYMEEER NFTTEQVTAM LLSKLKETAE SVLKKPVVDC VVSVPCFYTD AERRSVMDAT QIAGLNCLRL MNETTAVALA YGIYKQDLPA LEEKPRNVVF VDMGHSAYQV SVCAFNRGKL KVLATAFDTT LGGRKFDEVL VNHFCEEFGK KYKLDIKSKI RALLRLSQEC EKLKKLMSAN ASDLPLSIEC FMNDVDVSGT MNRGKFLEMC NDLLARVEPP LRSVLEQTKL KKEDIYAVEI VGGATRIPAV KEKISKFFGK ELSTTLNADE AVTRGCALQC AILSPAFKVR EFSITDVVPY PISLRWNSPA EEGSSDCEVF SKNHAAPFSK VLTFYRKEPF TLEAYYSSPQ DLPYPDPAIA QFSVQKVTPQ SDGSSSKVKV KVRVNVHGIF SVSSASLVEV HKSEENEEPM ETDQNAKEEE KMQVDQEEPH VEEQQQQTPA ENKAESEEME TSQAGSKDKK MDQPPQAKKA KVKTSTVDLP IENQLLWQID REMLNLYIEN EGKMIMQDKL EKERNDAKNA VEEYVYEMRD KLSGEYEKFV SEDDRNSFTL KLEDTENWLY EDGEDQPKQV YVDKLAELKN LGQPIKIRFQ ESEERPKLFE ELGKQIQQYM KIISSFKNKE DQYDHLDAAD MTKVEKSTNE AMEWMNNKLN LQNKQSLTMD PVVKSKEIEA KIKELTSTCS PIISKPKPKV EPPKEEQKNA EQNGPVDGQG DNPGPQAAEQ GTDTAVPSDS DKKLPEMDID
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human HSPA4. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
94,331 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (132387662..132440709). Location: 5q31.1
OMIM
601113
3D Structure
ModBase 3D Structure for P34932
Immunogen
Full length human HSPA4, aa1-840 (AAI10862.1).

Product Categories/Family for anti-HSPA4 antibody

Antibodies; Abs to Heat Shock Proteins
Applications Tested/Suitable for anti-HSPA4 antibody
Western Blot (WB)
Application Notes for anti-HSPA4 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-HSPA4 antibody

HSPA4 rabbit polyclonal antibody. Western Blot analysis of HSPA4 expression in mouse spleen.
Rabbit Anti-HSPA4 Polyclonal Antibody – Cat# MBS644138

Western Blot (WB) of anti-HSPA4 antibody

HSPA4 rabbit polyclonal antibody. Western Blot analysis of HSPA4 expression in Jurkat.
Rabbit Anti-HSPA4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS644138

Western Blot (WB) of anti-HSPA4 antibody

Western Blot analysis of HSPA4 expression in transfected 293T cell line by HSPA4 polyclonal antibody. Lane 1: HSPA4 transfected lysate (94.3kD). Lane 2: Non-transfected lysate.
Rabbit Anti-HSPA4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS644138

Other Notes

Small volumes of anti-HSPA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSPA4 purchase

MBS644138 is an antibody targeting HSPA4. Also known as HSPA4 (Heat Shock 70kD Protein 4, Heat Shock 70-related Protein APG-2, HSP70RY, APG2). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HSPA4. It may not necessarily be applicable to this product.

NCBI GI #
38327039
NCBI GeneID
3308
NCBI Accession #
NP_002145.3
UniProt Primary Accession #
P34932
UniProt Secondary Accession #
O95756; Q2TAL4
UniProt Related Accession #
P34932
GenBank Nucleotide #
NM_002154.3
NCBI Official Full Name
heat shock 70 kDa protein 4
NCBI Official Synonym Full Names
heat shock 70kDa protein 4
NCBI Official Symbol
HSPA4
NCBI Official Synonym Symbols
RY; APG-2; HSPH2; hsp70; hsp70RY; HS24/P52
UniProt Protein Name
Heat shock 70 kDa protein 4
UniProt Synonym Protein Names
HSP70RY; Heat shock 70-related protein APG-2
Protein Family
Heat shock 70 kDa protein
UniProt Gene Name
HSPA4
UniProt Synonym Gene Names
APG2
UniProt Entry Name
HSP74_HUMAN
NCBI Protein Information
heat shock 70 kDa protein 4; hsp70 RY; heat shock 70kD protein 4; heat shock protein, 110 kDa; heat shock 70-related protein APG-2

UniProt Comments for HSPA4

HSP70RY: Interacts with TJP1/ZO-1. Belongs to the heat shock protein 70 family.

Protein type: Heat shock protein; Chaperone

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: mitochondrion; cytosol

Molecular Function: ATP binding

Biological Process: chaperone-mediated protein complex assembly; protein import into mitochondrial outer membrane; response to unfolded protein
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Research Articles on HSPA4

1. Both HSP27 and HSP70 impact on the biological behaviour of urothelial carcinomas of the urinary bladder.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HSPA4 antibody

 Reference Product  PubMed Publications
 HSF1 antibody  >2 publications with HSPA4 and HSF1
 TP53 antibody  >1 publications with HSPA4 and TP53
 HSP90AA1 antibody  >1 publications with HSPA4 and HSP90AA1

Pathways associated with anti-HSPA4 antibody

 Products by Pathway  Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Parkin-Ubiquitin Proteasomal System Pathway antibodies  Parkin-Ubiquitin Proteasomal System Pathway Diagram
 Validated Targets Of C-MYC Transcriptional Activation Pathway antibodies  Validated Targets Of C-MYC Transcriptional Activation Pathway Diagram

Diseases associated with anti-HSPA4 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13 publications with HSPA4 and Neoplasms
 Cardiovascular Diseases Antibodies  >11 publications with HSPA4 and Cardiovascular Diseases
 Brain Diseases Antibodies  >5 publications with HSPA4 and Brain Diseases
 Nervous System Diseases Antibodies  >5 publications with HSPA4 and Nervous System Diseases
 Adenocarcinoma Antibodies  >3 publications with HSPA4 and Adenocarcinoma
 Infertility, Male Antibodies  >3 publications with HSPA4 and Infertility, Male
 Carcinoma, Hepatocellular Antibodies  >3 publications with HSPA4 and Carcinoma, Hepatocellular
 Fibrosis Antibodies  >2 publications with HSPA4 and Fibrosis
 Liver Diseases Antibodies  >2 publications with HSPA4 and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with HSPA4 and Liver Neoplasms

Organs/Tissues associated with anti-HSPA4 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >10 publications with HSPA4 and Blood
 Brain Antibodies  >10 publications with HSPA4 and Brain
 Heart Antibodies  >6 publications with HSPA4 and Heart
 Testis Antibodies  >4 publications with HSPA4 and Testis
 Bone Antibodies  >4 publications with HSPA4 and Bone
 Liver Antibodies  >4 publications with HSPA4 and Liver
 Lung Antibodies  >3 publications with HSPA4 and Lung
 Kidney Antibodies  >3 publications with HSPA4 and Kidney
 Embryonic Tissue Antibodies  >3 publications with HSPA4 and Embryonic Tissue
 Muscle Antibodies  >3 publications with HSPA4 and Muscle
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