Mouse Anti-ANKRD17 Polyclonal Antibody – Cat# MBS644221

Western Blot analysis of ANKRD17 expression in transfected 293T cell line by ANKRD17 polyclonal antibody. Lane1: ANKRD17 transfected lysate (82.61kD). Lane2: Non-transfected lysate.

ANKRD17 Antibody – Mouse Polyclonal

Name: ANKRD17 Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS644221
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644221

Earliest specific in situ marker of hepatic differentiation during embryogenesis, useful for characterization of inductive events involved in hepatic specification. Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth… More details

$880 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ANKRD17, Polyclonal Antibody

Full Product Name

ANKRD17 (Ankyrin Repeat Domain-containing Protein 17, Gene Trap Ankyrin Repeat Protein, Serologically Defined Breast Cancer Antigen NY-BR-16, GTAR, KIAA0697)

Product Gene Name

anti-ANKRD17 antibody

Product Synonym Names

Anti -ANKRD17 (Ankyrin Repeat Domain-containing Protein 17, Gene Trap Ankyrin Repeat Protein, Serologically Defined Breast Cancer Antigen NY-BR-16, GTAR, KIAA0697)

Immunogen Sequence

MEKATVPVAA ATAAEGEGSP PAVAAVAGPP AAAEVGGGVG GSSRARSASS PRGMVRVCDL LLKKKPPQQQ HHKAKRNRTC RPPSSSESSS DSDNSGGGGG GGGGGGGGGG TSSNNSEEEE DDDDEEEEVS EVESFILDQD DLENPMLETA SKLLLSGTAD GADLRTVDPE TQARLEALLE AAGIGKLSTA DGKAFADPEV LRRLTSSVSC ALDEAAAALT RMRAESTANA GQSDNRSLAE ACSEGDVNAV RKLLIEGRSV NEHTEEGESL LCLACSAGYY ELAQVLLAMH ANVEDRGIKG DITPLMAAAN GGHVKIVKLL LAHKADVNAQ SSTGNTALTY ACAGGYVDVV KVLLESGASI EDHNENGHTP LMEAGSAGHV EVARLLLENG AGINTHSNEF KESALTLACY KGHLEMVRFL LEAGADQEHK TDEMHTALME ACMDGHVEVA RLLLDSGAQV NMPADSFESP LTLAACGGHV ELAALLIERG ASLEEVNDEG YTPLMEAARE GHEEMVALLL GQGANINAQT EETQETALTL ACCGGFLEVA DFLIKAGADI ELGCSTPLME AAQEGHLELV KYLLAAGANV HATTATGDTA LTYACENGHT DVADVLLQAG ADLEHESEGG RTPLMKAARA GHVCTVQFLI SKGANVNRTT ANNDHTVLSL ACAGGHLAVV ELLLAHGADP THRLKDGSTM LIEAAKGGHT SVVCYLLDYP NNLLSAPPPD VTQLTPPSHD LTDNIFPRLV C

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human ANKRD17.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

274,258 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (73940502..74124858, complement). Location: 4q13.3

3D Structure

ModBase 3D Structure for O75179

Immunogen

Full length human ANKRD17, aa1-751 (AAH43394.1).

Product Categories/Family for anti-ANKRD17 antibody

Antibodies; Abs to Membrane Proteins

Applications Tested/Suitable for anti-ANKRD17 antibody

Western Blot (WB)

Application Notes for anti-ANKRD17 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-ANKRD17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ANKRD17 purchase

MBS644221 is an antibody targeting ANKRD17. Also known as ANKRD17 (Ankyrin Repeat Domain-containing Protein 17, Gene Trap Ankyrin Repeat Protein, Serologically Defined Breast Cancer Antigen NY-BR-16, GTAR, KIAA0697). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ANKRD17. It may not necessarily be applicable to this product.

NCBI GI #

38683816

NCBI GeneID

26057

NCBI Accession #

NP_942592.1

UniProt Primary Accession #

O75179

UniProt Secondary Accession #

Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9; G5E964

UniProt Related Accession #

O75179

GenBank Nucleotide #

NM_198889.1

NCBI Official Full Name

ankyrin repeat domain-containing protein 17 isoform b

NCBI Official Synonym Full Names

ankyrin repeat domain 17

NCBI Official Symbol

ANKRD17

NCBI Official Synonym Symbols

GTAR; NY-BR-16

UniProt Protein Name

Ankyrin repeat domain-containing protein 17

UniProt Synonym Protein Names

Gene trap ankyrin repeat protein; Serologically defined breast cancer antigen NY-BR-16

Protein Family

Ankyrin repeat domain-containing protein

UniProt Gene Name

ANKRD17

UniProt Synonym Gene Names

GTAR; KIAA0697

UniProt Entry Name

ANR17_HUMAN

NCBI Protein Information

ankyrin repeat domain-containing protein 17; gene trap ankyrin repeat protein; serologically defined breast cancer antigen NY-BR-16

NCBI Summary for ANKRD17

This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies in mice suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for ANKRD17

ANKRD17: the earliest specific in situ marker of hepatic differentiation during embryogenesis, useful for characterization of inductive events involved in hepatic specification. Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease). Interacts with VP1 capsid protein of enterovirus 71 (EV71). Five alternatively processed human isoforms have been described.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: membrane; cytoplasm; nucleus; chromatin

Molecular Function: protein binding; chromatin binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; viral reproduction; defense response to bacterium; positive regulation of cell cycle; innate immune response; negative regulation of smooth muscle cell differentiation; blood vessel maturation; regulation of DNA replication

Research Articles on ANKRD17

1. A novel function for Ankrd17 in Nod1 and Nod2 mediated anti-bacterial innate immune pathways.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ANKRD17 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with ANKRD17 and Neoplasms
Hemorrhage Antibodies	>1 publications with ANKRD17 and Hemorrhage
Carcinoma Antibodies	>1 publications with ANKRD17 and Carcinoma
Adenocarcinoma Antibodies	>1 publications with ANKRD17 and Adenocarcinoma
Inflammation Antibodies	>1 publications with ANKRD17 and Inflammation
Intestinal Neoplasms Antibodies	>1 publications with ANKRD17 and Intestinal Neoplasms
Liver Neoplasms Antibodies	>1 publications with ANKRD17 and Liver Neoplasms
Liver Diseases Antibodies	>1 publications with ANKRD17 and Liver Diseases

Organs/Tissues associated with anti-ANKRD17 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with ANKRD17 and Brain
Bone Antibodies	>1 publications with ANKRD17 and Bone
Testis Antibodies	>1 publications with ANKRD17 and Testis