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SCD Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644369

Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O2 and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and… More details

$835 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SCD, Polyclonal Antibody
Full Product Name
SCD, CT (Acyl-CoA Desaturase, Delta(9)-desaturase, Delta-9 Desaturase, Fatty Acid Desaturase, Stearoyl-CoA Desaturase)
Product Gene Name
anti-SCD antibody
Product Synonym Names
Anti -SCD, CT (Acyl-CoA Desaturase, Delta(9)-desaturase, Delta-9 Desaturase, Fatty Acid Desaturase, Stearoyl-CoA Desaturase)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SCD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
41,523 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (102106772..102124588). Location: 10q24.31
OMIM
604031
3D Structure
ModBase 3D Structure for O00767
Immunogen
Synthetic peptide corresponding to C-RIKRTGDGNYKSG from C-terminus of human SCD.

Product Categories/Family for anti-SCD antibody

Antibodies; Abs to Enzymes
Applications Tested/Suitable for anti-SCD antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-SCD antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:64,000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-SCD antibody

Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Goat Anti-SCD Polyclonal Antibody – Cat# MBS644369

Immunohistochemistry (IHC) of anti-SCD antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Goat Anti-SCD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS644369

Other Notes

Small volumes of anti-SCD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCD purchase

MBS644369 is an antibody targeting SCD. Also known as SCD, CT (Acyl-CoA Desaturase, Delta(9)-desaturase, Delta-9 Desaturase, Fatty Acid Desaturase, Stearoyl-CoA Desaturase). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for SCD. It may not necessarily be applicable to this product.

NCBI GI #
13543284
NCBI GeneID
6319
NCBI Accession #
AAH05807.1
UniProt Primary Accession #
O00767
UniProt Secondary Accession #
Q16150; Q53GR9; Q5W037; Q5W038; Q6GSS4; Q96KF6; Q9BS07; Q9Y695; B2R5U0; D3DR68
UniProt Related Accession #
O00767
NCBI Official Full Name
SCD protein
NCBI Official Synonym Full Names
stearoyl-CoA desaturase (delta-9-desaturase)
NCBI Official Symbol
SCD
NCBI Official Synonym Symbols
SCD1; FADS5; SCDOS; MSTP008
UniProt Protein Name
Acyl-CoA desaturase
UniProt Synonym Protein Names
Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase; Stearoyl-CoA desaturase
Protein Family
Acyl-CoA desaturase
UniProt Gene Name
SCD
UniProt Synonym Gene Names
Delta-9 desaturase
UniProt Entry Name
ACOD_HUMAN
NCBI Protein Information
acyl-CoA desaturase; delta-9 desaturase; delta-9-desaturase; delta(9)-desaturase; fatty acid desaturase; predicted protein of HQ0998; stearoyl-CoA desaturase opposite strand

NCBI Summary for SCD

This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Feb 2012]
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UniProt Comments for SCD

SCD: Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Belongs to the fatty acid desaturase family.

Protein type: Lipid Metabolism - unsaturated fatty acid biosynthesis; Oxidoreductase; EC 1.14.19.1; Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 10q24.31

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: iron ion binding; stearoyl-CoA 9-desaturase activity

Biological Process: fatty acid biosynthetic process
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Research Articles on SCD

1. Patients with primary breast cancers expressing high SCD1 levels had significantly shorter relapse-free survival and overall survival in multivariable analysis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SCD antibody

 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 SREBF And MiR33 In Cholesterol And Lipid Homeostasis Pathway antibodies  SREBF And MiR33 In Cholesterol And Lipid Homeostasis Pathway Diagram
 SREBP Signalling Pathway antibodies  SREBP Signalling Pathway Diagram
 Oleate Biosynthesis II (animals) Pathway antibodies  Oleate Biosynthesis II (animals) Pathway Diagram

Diseases associated with anti-SCD antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1762 publications with SCD and Cardiovascular Diseases
 Heart Diseases Antibodies  >1353 publications with SCD and Heart Diseases
 Pain Antibodies  >576 publications with SCD and Pain
 Heart Failure Antibodies  >371 publications with SCD and Heart Failure
 Myocardial Infarction Antibodies  >346 publications with SCD and Myocardial Infarction
 Hypertension Antibodies  >279 publications with SCD and Hypertension
 Inflammation Antibodies  >250 publications with SCD and Inflammation
 Neoplasms Antibodies  >239 publications with SCD and Neoplasms
 Fatty Liver Antibodies  >194 publications with SCD and Fatty Liver
 Necrosis Antibodies  >141 publications with SCD and Necrosis

Organs/Tissues associated with anti-SCD antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1836 publications with SCD and Blood
 Heart Antibodies  >1194 publications with SCD and Heart
 Vascular Antibodies  >467 publications with SCD and Vascular
 Bone Antibodies  >395 publications with SCD and Bone
 Liver Antibodies  >371 publications with SCD and Liver
 Brain Antibodies  >361 publications with SCD and Brain
 Mouth Antibodies  >343 publications with SCD and Mouth
 Muscle Antibodies  >302 publications with SCD and Muscle
 Kidney Antibodies  >217 publications with SCD and Kidney
 Lung Antibodies  >200 publications with SCD and Lung
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