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AMIGO2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644378

A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane… More details

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Product Overview

Online Datasheet in PDF
Product Name
ALI1 (AMIGO2), Polyclonal Antibody
Full Product Name
ALI1 (Amphoterin-induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in Gastric Adenocarcinomas, DEGA, AMIGO2)
Product Gene Name
Product Synonym Names
Anti -ALI1 (Amphoterin-induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in Gastric Adenocarcinomas, DEGA, AMIGO2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat0
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes mouse Alivin 1. Species Crossreactivity
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
57,934 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (47469490..47473734, complement). Location: 12q13.11
3D Structure
ModBase 3D Structure for Q86SJ2
Immunogen
Synthetic peptide corresponding to aa449-464 [TGDASADDRKAGKRVV] of mouse and rat Alivin 1.
Applications Tested/Suitable for anti-AMIGO2 antibody
Western Blot (WB)
Application Notes for anti-AMIGO2 antibody
Suitable for use in Western Blot.
Dilution: Western Blot: 1:500

Western Blot (WB) of anti-AMIGO2 antibody

Western blot analysis of Alivin 1 using MBS644378 at 1:500 dilution on 50ug of mouse brain lysate.
Rabbit Anti-AMIGO2 Polyclonal Antibody – Cat# MBS644378

Other Notes

Small volumes of anti-AMIGO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMIGO2 purchase

MBS644378 is an antibody targeting AMIGO2. Also known as ALI1 (Amphoterin-induced Protein 2, AMIGO-2, Alivin-1, Differentially Expressed in Gastric Adenocarcinomas, DEGA, AMIGO2). Reactive in Mouse, Rat0. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AMIGO2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
amphoterin-induced protein 2
NCBI Official Synonym Full Names
adhesion molecule with Ig-like domain 2
NCBI Official Symbol
AMIGO2
NCBI Official Synonym Symbols
ALI1; DEGA; AMIGO-2
UniProt Protein Name
Amphoterin-induced protein 2
UniProt Synonym Protein Names
AMIGO-2; Alivin-1; Differentially expressed in gastric adenocarcinomas
UniProt Gene Name
AMIGO2
UniProt Synonym Gene Names
ALI1; DEGA
UniProt Entry Name
AMGO2_HUMAN
NCBI Protein Information
amphoterin-induced protein 2; alivin 1; amphoterin induced gene 2; transmembrane protein AMIGO2; differentially expressed in gastric adenocarcinoma; differentially expressed in gastric adenocarcinomas

UniProt Comments for AMIGO2

AMIGO2: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. Belongs to the immunoglobulin superfamily. AMIGO family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q13.11

Cellular Component: plasma membrane; integral to membrane; nucleus

Molecular Function: protein binding

Biological Process: heterophilic cell adhesion; negative regulation of programmed cell death; brain development; homophilic cell adhesion; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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