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MGAT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS644458

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MGAT1, Polyclonal Antibody
Full Product Name
MGAT1, ID (MGAT1, GGNT1, GLCT1, GLYT1, MGAT, Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I)
Product Gene Name
anti-MGAT1 antibody
Product Synonym Names
Anti -MGAT1, ID (MGAT1, GGNT1, GLCT1, GLYT1, MGAT, Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
50,878 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (180217541..180237939, complement). Location: 5q35
OMIM
160995
3D Structure
ModBase 3D Structure for P26572
Immunogen
MGAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human MGAT1.

Product Categories/Family for anti-MGAT1 antibody

Antibodies; Abs to Enzymes; Glycosyltransferase
Applications Tested/Suitable for anti-MGAT1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-MGAT1 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-MGAT1 antibody

MGAT1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MGAT1 antibody detected the MGAT1 protein (arrow).
Rabbit Anti-MGAT1 Polyclonal Antibody – Cat# MBS644458

Other Notes

Small volumes of anti-MGAT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MGAT1 purchase

MBS644458 is an antibody targeting MGAT1. Also known as MGAT1, ID (MGAT1, GGNT1, GLCT1, GLYT1, MGAT, Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MGAT1. It may not necessarily be applicable to this product.

NCBI GI #
48145839
NCBI GeneID
4245
NCBI Accession #
CAG33142.1
UniProt Primary Accession #
P26572
UniProt Secondary Accession #
Q6IBE3; A8K404; D3DWR1
UniProt Related Accession #
P26572
NCBI Official Full Name
MGAT1
NCBI Official Synonym Full Names
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
NCBI Official Symbol
MGAT1
NCBI Official Synonym Symbols
MGAT; GLCT1; GLYT1; GNT-1; GNT-I; GLCNAC-TI
UniProt Protein Name
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
UniProt Synonym Protein Names
N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I
Protein Family
2-acylglycerol O-acyltransferase
UniProt Gene Name
MGAT1
UniProt Synonym Gene Names
GGNT1; GLCT1; GLYT1; MGAT; GNT-I; GlcNAc-T I
UniProt Entry Name
MGAT1_HUMAN
NCBI Protein Information
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; glcNAc-T I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I

UniProt Comments for MGAT1

MGAT1: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Belongs to the glycosyltransferase 13 family.

Protein type: Membrane protein, integral; Glycan Metabolism - N-glycan biosynthesis; Transferase; EC 2.4.1.101

Chromosomal Location of Human Ortholog: 5q35

Cellular Component: Golgi membrane; membrane; integral to membrane; vesicle

Molecular Function: acetylglucosaminyltransferase activity; metal ion binding; alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

Biological Process: cellular protein metabolic process; in utero embryonic development; carbohydrate metabolic process; protein amino acid glycosylation; UDP-N-acetylglucosamine catabolic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
Show more

Research Articles on MGAT1

1. analysis of suppression of cancer progression by MGAT1 shRNA knockdown

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MGAT1 antibody

 Reference Product  PubMed Publications
 MGAT3 antibody  >13 publications with MGAT1 and MGAT3
 MGAT5 antibody  >5 publications with MGAT1 and MGAT5
 MAN2A1 antibody  >1 publications with MGAT1 and MAN2A1

Pathways associated with anti-MGAT1 antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 N-glycan Trimming And Elongation In The Cis-Golgi Pathway antibodies  N-glycan Trimming And Elongation In The Cis-Golgi Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 Transport To The Golgi And Subsequent Modification Pathway antibodies  Transport To The Golgi And Subsequent Modification Pathway Diagram
 WNT Ligand Biogenesis And Trafficking Pathway antibodies  WNT Ligand Biogenesis And Trafficking Pathway Diagram

Diseases associated with anti-MGAT1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >10 publications with MGAT1 and Nervous System Diseases
 Death Antibodies  >5 publications with MGAT1 and Death
 Learning Disorders Antibodies  >2 publications with MGAT1 and Learning Disorders
 Weight Loss Antibodies  >2 publications with MGAT1 and Weight Loss
 Fatty Liver Antibodies  >2 publications with MGAT1 and Fatty Liver
 Carcinoma Antibodies  >1 publications with MGAT1 and Carcinoma
 Inflammation Antibodies  >1 publications with MGAT1 and Inflammation
 Neoplasm Metastasis Antibodies  >1 publications with MGAT1 and Neoplasm Metastasis
 Prostatic Diseases Antibodies  >1 publications with MGAT1 and Prostatic Diseases
 Liver Diseases Antibodies  >1 publications with MGAT1 and Liver Diseases

Organs/Tissues associated with anti-MGAT1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with MGAT1 and Brain
 Blood Antibodies  >8 publications with MGAT1 and Blood
 Kidney Antibodies  >8 publications with MGAT1 and Kidney
 Liver Antibodies  >8 publications with MGAT1 and Liver
 Intestine Antibodies  >4 publications with MGAT1 and Intestine
 Embryonic Tissue Antibodies  >3 publications with MGAT1 and Embryonic Tissue
 Ovary Antibodies  >3 publications with MGAT1 and Ovary
 Stomach Antibodies  >3 publications with MGAT1 and Stomach
 Testis Antibodies  >2 publications with MGAT1 and Testis
 Lung Antibodies  >2 publications with MGAT1 and Lung
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