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NAA20 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645371

NAT5 is a component of N-acetyltransferase complex B (NatB). Human NatB performs cotranslational N(alpha)-terminal acetylation of methionine residues when they are followed by asparagine (Starheim et al., 2008 [PubMed 18570629]).[supplied by OMIM]. More details

$895 / 0.2 mL +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NAT5 (NAA20), Polyclonal Antibody
Full Product Name
NAT5, CT (NAA20, NAT5, N-alpha-acetyltransferase 20, N-acetyltransferase 5, N-terminal acetyltransferase B complex catalytic subunit NAA20, N-terminal acetyltransferase B complex catalytic subunit NAT5, NatB catalytic subunit)
Product Gene Name
Product Synonym Names
Anti -NAT5, CT (NAA20, NAT5, N-alpha-acetyltransferase 20, N-acetyltransferase 5, N-terminal acetyltransferase B complex catalytic subunit NAA20, N-terminal acetyltransferase B complex catalytic subunit NAT5, NatB catalytic subunit)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
20,368 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (19997934..20014273). Location: 20p11.23
OMIM
610833
3D Structure
ModBase 3D Structure for P61599
Immunogen
NAT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the C-terminal region of human NAT5.
Applications Tested/Suitable for anti-NAA20 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-NAA20 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-NAA20 antibody

NAT5 Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NAT5 antibody detected the NAT5 protein (arrow).
Rabbit Anti-NAA20 Polyclonal Antibody – Cat# MBS645371

Other Notes

Small volumes of anti-NAA20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NAA20 purchase

MBS645371 is an antibody targeting NAA20. Also known as NAT5, CT (NAA20, NAT5, N-alpha-acetyltransferase 20, N-acetyltransferase 5, N-terminal acetyltransferase B complex catalytic subunit NAA20, N-terminal acetyltransferase B complex catalytic subunit NAT5, NatB catalytic subunit). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NAA20. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
N-alpha-acetyltransferase 20 isoform c
NCBI Official Synonym Full Names
N(alpha)-acetyltransferase 20, NatB catalytic subunit
NCBI Official Symbol
NAA20
NCBI Official Synonym Symbols
NAT3; NAT5; dJ1002M8.1
UniProt Protein Name
N-alpha-acetyltransferase 20
UniProt Synonym Protein Names
Methionine N-acetyltransferase; N-acetyltransferase 5; N-terminal acetyltransferase B complex catalytic subunit NAA20; N-terminal acetyltransferase B complex catalytic subunit NAT5; NatB complex subunit NAT5; NatB catalytic subunit
UniProt Gene Name
NAA20
UniProt Synonym Gene Names
NAT5; NatB complex subunit NAT5
UniProt Entry Name
NAA20_HUMAN
NCBI Protein Information
N-alpha-acetyltransferase 20; natB catalytic subunit; natB complex subunit NAT5; N-acetyltransferase 3 homolog; methionine N-acetyltransferase; N-acetyltransferase 5 (GCN5-related, putative); N-terminal acetyltransferase complex ARD1 subunit; N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae); N-alpha-acetyltransferase 20, NatB catalytic subunit; N-terminal acetyltransferase B complex catalytic subunit NAT5; N-terminal acetyltransferase B complex catalytic subunit NAA20; N-acetyltransferase 5, ARD1 subunit (arrest-defective 1, S. cerevisiae, homolog)

NCBI Summary for NAA20

NAT5 is a component of N-acetyltransferase complex B (NatB). Human NatB performs cotranslational N(alpha)-terminal acetylation of methionine residues when they are followed by asparagine (Starheim et al., 2008 [PubMed 18570629]).[supplied by OMIM, Apr 2009]

UniProt Comments for NAA20

NAA20: Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration. Belongs to the acetyltransferase family. ARD1 subfamily.

Protein type: Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - phenylalanine; Acetyltransferase; Lipid Metabolism - glycerophospholipid; EC 2.3.1.88

Chromosomal Location of Human Ortholog: 20p11.23

Cellular Component: cytoplasm; intracellular; nucleus

Molecular Function: peptide alpha-N-acetyltransferase activity

Biological Process: N-terminal peptidyl-methionine acetylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NAA20 antibody

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