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TBC1D20 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645430

MBS645430 is an antibody targeting TBC1D20. Also known as TBC1D20, CT (TBC1D20, C20orf140, TBC1 domain family member 20). Reactive in Human. Host: Rabbit. TBC1D20 may act as a GTPase-activating protein for Rab family protein(s). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TBC1D20, Polyclonal Antibody
Full Product Name
TBC1D20, CT (TBC1D20, C20orf140, TBC1 domain family member 20)
Product Gene Name
Product Synonym Names
Anti -TBC1D20, CT (TBC1D20, C20orf140, TBC1 domain family member 20)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
45,855 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (416124..443187, complement). Location: 20p13
OMIM
611663
3D Structure
ModBase 3D Structure for Q96BZ9
Immunogen
TBC1D20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-363 amino acids from the C-terminal region of human TBC1D20.
Applications Tested/Suitable for anti-TBC1D20 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-TBC1D20 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-TBC1D20 antibody

TBC1D20 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TBC1D20 antibody detected the TBC1D20 protein (arrow).
Rabbit Anti-TBC1D20 Polyclonal Antibody – Cat# MBS645430

Other Notes

Small volumes of anti-TBC1D20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TBC1D20. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TBC1 domain family member 20
NCBI Official Synonym Full Names
TBC1 domain family, member 20
NCBI Official Symbol
TBC1D20
NCBI Official Synonym Symbols
C20orf140
UniProt Protein Name
TBC1 domain family member 20
Protein Family
UniProt Gene Name
TBC1D20
UniProt Synonym Gene Names
C20orf140
UniProt Entry Name
TBC20_HUMAN
NCBI Protein Information
TBC1 domain family member 20

NCBI Summary for TBC1D20

This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
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UniProt Comments for TBC1D20

TBC1D20: May act as a GTPase-activating protein for Rab family protein(s). 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; GAPs, Rab; GAPs; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: endoplasmic reticulum membrane; nuclear membrane; endoplasmic reticulum; integral to Golgi membrane

Molecular Function: protein binding; Rab GTPase binding

Biological Process: acrosome formation; ER to Golgi vesicle-mediated transport; positive regulation of viral protein levels in host cell; virus assembly; Golgi organization and biogenesis

Disease: Warburg Micro Syndrome 4
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TBC1D20 antibody

Diseases associated with anti-TBC1D20 antibody

Organs/Tissues associated with anti-TBC1D20 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >1 publications with TBC1D20 and Skin
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