Goat Anti-ATAD5 Polyclonal Antibody – Cat# MBS646188

ATAD5 Antibody – Goat Polyclonal

Name: ATAD5 Antibody; Polyclonal; Goat; Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS646188
Price: 610 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS646188

Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A… More details

$610 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Atad5, Polyclonal Antibody

Full Product Name

Atad5 (ATPase Family AAA Domain-containing Protein 5, Chromosome Fragility-associated Gene 1 Protein, Frag1)

Product Gene Name

anti-ATAD5 antibody

Product Synonym Names

Anti -Atad5 (ATPase Family AAA Domain-containing Protein 5, Chromosome Fragility-associated Gene 1 Protein, Frag1)

Clonality

Polyclonal

Host

Goat

Species Reactivity

Mouse, Rat

Form/Format

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes Atad5. Species sequence homology: Mouse and rat.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

207,570 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (29159020..29222295). Location: 17q11.2

OMIM

609534

3D Structure

ModBase 3D Structure for Q96QE3

Immunogen

Synthetic peptide corresponding to C-QSKDQPLRKSQK, from Atad5, at the internal region of the protein (NP_001025027.1).

Product Categories/Family for anti-ATAD5 antibody

Antibodies; Abs to Enzymes; ATPase

Applications Tested/Suitable for anti-ATAD5 antibody

ELISA (EL/EIA)

Application Notes for anti-ATAD5 antibody

Suitable for use in ELISA.
Dilution: ELISA: 1:64,000

Other Notes

Small volumes of anti-ATAD5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATAD5 purchase

MBS646188 is an antibody targeting ATAD5. Also known as Atad5 (ATPase Family AAA Domain-containing Protein 5, Chromosome Fragility-associated Gene 1 Protein, Frag1). Reactive in Mouse, Rat. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for ATAD5. It may not necessarily be applicable to this product.

NCBI GI #

26080431

NCBI GeneID

79915

NCBI Accession #

NP_079133.3

UniProt Primary Accession #

Q96QE3

UniProt Secondary Accession #

Q05DH0; Q69YR6; Q9H9I1

UniProt Related Accession #

Q96QE3

GenBank Nucleotide #

NM_024857.3

NCBI Official Full Name

ATPase family AAA domain-containing protein 5

NCBI Official Synonym Full Names

ATPase family, AAA domain containing 5

NCBI Official Symbol

ATAD5

NCBI Official Synonym Symbols

ELG1; FRAG1; C17orf41

UniProt Protein Name

ATPase family AAA domain-containing protein 5

UniProt Synonym Protein Names

Chromosome fragility-associated gene 1 protein

Protein Family

ATPase family AAA domain-containing protein

UniProt Gene Name

ATAD5

UniProt Synonym Gene Names

C17orf41; FRAG1

UniProt Entry Name

ATAD5_HUMAN

NCBI Protein Information

ATPase family AAA domain-containing protein 5; chromosome fragility associated gene 1; chromosome fragility-associated gene 1 protein; enhanced level of genomic instability 1 homolog

UniProt Comments for ATAD5

Function: Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis. Ref.3

Subunit structure: Interacts with RB1 predominantly in G1 phase via its LXCXE motif. Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents. Interacts with BRD4. Ref.3 Ref.13

Subcellular location: Nucleus

Potential.

Post-translational modification: ATR may stimulate the RAD9A dissociation.

Sequence similarities: Belongs to the AAA ATPase family.

Sequence caution: The sequence AAH15051.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.The sequence BAB14248.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Research Articles on ATAD5

1. ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA-unloading activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ATAD5 antibody

Reference Product	PubMed Publications
PCNA antibody	>8 publications with ATAD5 and PCNA
USP1 antibody	>3 publications with ATAD5 and USP1

Diseases associated with anti-ATAD5 antibody

Disease Name	Pubmed Publications
Anemia Antibodies	>2 publications with ATAD5 and Anemia
Nervous System Diseases Antibodies	>1 publications with ATAD5 and Nervous System Diseases