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ALDH8A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6462380

MBS6462380 is an antibody targeting ALDH8A1. Also known as ALDH8A1, CT (Aldehyde Dehydrogenase Family 8 Member A1, Aldehyde Dehydrogenase 12, ALDH12) (MaxLight 490). Reactive in Human. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ALDH8A1, Polyclonal Antibody
Full Product Name
ALDH8A1, CT (Aldehyde Dehydrogenase Family 8 Member A1, Aldehyde Dehydrogenase 12, ALDH12) (MaxLight 490)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human ALDH8A1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
53.271
OMIM
606467
3D Structure
ModBase 3D Structure for Q9H2A2
Immunogen
Synthetic peptide selected from the C-terminal region of human ALDH8A1 (KLH).
Conjugate
MaxLight490
Note
Preservative Free

Product Categories/Family for anti-ALDH8A1 antibody

Applications Tested/Suitable for anti-ALDH8A1 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-ALDH8A1 antibody
IHC: 1:10-1:50
FLISA: 1:1,000
WB: 1:50-1:100
Applications are based on unconjugated antibody.

Product References and Citations for anti-ALDH8A1 antibody

1. Lin, M., J. Biol. Chem. 275(51), 40106-40112 (2000).

Other Notes

Small volumes of anti-ALDH8A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH8A1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
2-aminomuconic semialdehyde dehydrogenase isoform 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 8 family member A1
NCBI Official Symbol
ALDH8A1
NCBI Official Synonym Symbols
ALDH12; DJ352A20.2
UniProt Protein Name
Aldehyde dehydrogenase family 8 member A1
UniProt Synonym Protein Names
Aldehyde dehydrogenase 12
UniProt Gene Name
ALDH8A1
UniProt Synonym Gene Names
ALDH12
UniProt Entry Name
AL8A1_HUMAN
NCBI Protein Information
2-aminomuconic semialdehyde dehydrogenase

NCBI Summary for ALDH8A1

This gene encodes a member of the aldehyde dehydrogenase family of proteins. The encoded protein has been implicated in the synthesis of 9-cis-retinoic acid and in the breakdown of the amino acid tryptophan. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. In addition, this enzyme has been shown to catalyze the conversion of 2-aminomuconic semialdehyde to 2-aminomuconate in the kynurenine pathway of tryptophan catabolism. [provided by RefSeq, Jul 2018]
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UniProt Comments for ALDH8A1

ALDH8A1: Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro). Belongs to the aldehyde dehydrogenase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.2.1.-; Oxidoreductase

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: cytoplasm; intracellular

Molecular Function: aldehyde dehydrogenase (NAD) activity; retinal dehydrogenase activity

Biological Process: retinal metabolic process; 9-cis-retinoic acid biosynthetic process; retinoic acid metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALDH8A1 antibody

 Reference Product  PubMed Publications
 HBS1L antibody  >3 publications with ALDH8A1 and HBS1L

Organs/Tissues associated with anti-ALDH8A1 antibody

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