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FKBP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6476002

MBS6476002 is an antibody targeting FKBP2. Also known as FKBP2, NT (FK506-binding Protein 2, Peptidyl-prolyl cis-trans Isomerase FKBP2, PPIase FKBP2, Rotamase, Immunophilin FKBP13, 13kD FK506-binding Protein, 13kD FKBP, FKBP-13, FKBP13, FKBP-2) (Biotin).… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FKBP2, Polyclonal Antibody
Full Product Name
FKBP2, NT (FK506-binding Protein 2, Peptidyl-prolyl cis-trans Isomerase FKBP2, PPIase FKBP2, Rotamase, Immunophilin FKBP13, 13kD FK506-binding Protein, 13kD FKBP, FKBP-13, FKBP13, FKBP-2) (Biotin)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human FKBP2. Species Crossreactivity: mouse.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
16kDa
OMIM
186946
3D Structure
ModBase 3D Structure for P26885
Immunogen
Synthetic peptide selected from the N-terminal region of human FKBP2 (KLH).
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-FKBP2 antibody

Applications Tested/Suitable for anti-FKBP2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-FKBP2 antibody
WB: 1:50-1:100
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-FKBP2 antibody

Western blot analysis of FKBP2 antibody (N-term) in mouse cerebellum tissue lysates (35ug/lane). FKBP2 (arrow) was detected using the purified Pab.
Rabbit Anti-FKBP2 Polyclonal Antibody – Cat# MBS6476002

Immunohistochemistry (IHC) of anti-FKBP2 antibody

FKBP2 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human Colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-FKBP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6476002

Flow Cytometry (FC/FACS) of anti-FKBP2 antibody

FKBP2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-FKBP2 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6476002

Product References and Citations for anti-FKBP2 antibody

1. Padilla, P.I., Proc. Natl. Acad. Sci. USA 100(5), 2322-2327 (2003). 2. Bush, K.T., Biochem. J. 303(PT 3), 705-708 (1994).

Other Notes

Small volumes of anti-FKBP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FKBP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase FKBP2
NCBI Official Synonym Full Names
FKBP prolyl isomerase 2
NCBI Official Symbol
FKBP2
NCBI Official Synonym Symbols
PPIase; FKBP-13
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase FKBP2
UniProt Synonym Protein Names
13 kDa FK506-binding protein; 13 kDa FKBP; FKBP-13; FK506-binding protein 2; FKBP-2; Immunophilin FKBP13; Rotamase
Protein Family
UniProt Gene Name
FKBP2
UniProt Synonym Gene Names
FKBP13; PPIase FKBP2; 13 kDa FKBP; FKBP-13; FKBP-2
UniProt Entry Name
FKBP2_HUMAN
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase FKBP2

NCBI Summary for FKBP2

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
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UniProt Comments for FKBP2

FKBP2: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the FKBP-type PPIase family. FKBP2 subfamily.

Protein type: Endoplasmic reticulum; Isomerase; EC 5.2.1.8

Chromosomal Location of Human Ortholog: 11q13.1-q13.3

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum

Molecular Function: protein binding; FK506 binding; peptidyl-prolyl cis-trans isomerase activity

Biological Process: protein peptidyl-prolyl isomerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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