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DLGAP4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648519

May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. More details

$915 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DLGAP4, Polyclonal Antibody
Full Product Name
DLGAP4, ID (Disks Large-associated Protein 4, DAP-4, PSD-95/SAP90-binding Protein 4, SAP90/PSD-95-associated Protein 4, SAPAP-4, DAP4, KIAA0964, SAPAP4)
Product Gene Name
anti-Dlgap4 antibody
Product Synonym Names
Anti -DLGAP4, ID (Disks Large-associated Protein 4, DAP-4, PSD-95/SAP90-binding Protein 4, SAP90/PSD-95-associated Protein 4, SAPAP-4, DAP4, KIAA0964, SAPAP4)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human DLGAP4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
108,037 Da
Chromosome Location
Chromosome: 2; NC_000068.7 (156613705..156764363). Location: 2 H1; 2
3D Structure
ModBase 3D Structure for B1AZP2
Immunogen
Synthetic peptide corresponding to 13aa from near the center of human SAPAP4.

Product Categories/Family for anti-Dlgap4 antibody

Antibodies; Abs to Neuroscience
Applications Tested/Suitable for anti-Dlgap4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-Dlgap4 antibody
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 0.5-1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-Dlgap4 antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-DLGAP4 Polyclonal Antibody – Cat# MBS648519

Western Blot (WB) of anti-Dlgap4 antibody

Western blot analysis of DLGAP4 in SK-N-SH cell lysate with DLGAP4 antibody at 1ug/ml.
Rabbit Anti-DLGAP4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS648519

Other Notes

Small volumes of anti-Dlgap4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dlgap4 purchase

MBS648519 is an antibody targeting Dlgap4. Also known as DLGAP4, ID (Disks Large-associated Protein 4, DAP-4, PSD-95/SAP90-binding Protein 4, SAP90/PSD-95-associated Protein 4, SAPAP-4, DAP4, KIAA0964, SAPAP4). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Dlgap4. It may not necessarily be applicable to this product.

NCBI GI #
219841800
NCBI GeneID
228836
NCBI Accession #
AAI45396.1
UniProt Primary Accession #
B1AZP2
UniProt Secondary Accession #
Q3KQQ8; Q6PD44; Q6XBF1; Q80TN3; Q8R3U9; B1AZP3; B7ZNS1
UniProt Related Accession #
B1AZP2
NCBI Official Full Name
Dlgap4 protein
NCBI Official Synonym Full Names
discs, large homolog-associated protein 4 (Drosophila)
NCBI Official Symbol
Dlgap4
NCBI Official Synonym Symbols
DAP4; DAP-4; WBP16; Sapap4; SAPAP-4; AI225853; BC024558
UniProt Protein Name
Disks large-associated protein 4
UniProt Synonym Protein Names
PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4
Protein Family
Disks large-associated protein
UniProt Gene Name
Dlgap4
UniProt Synonym Gene Names
Kiaa0964; Sapap4; DAP-4; SAPAP-4
UniProt Entry Name
DLGP4_MOUSE
NCBI Protein Information
disks large-associated protein 4; WW domain-binding protein 16; PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4

NCBI Summary for Dlgap4

This gene encodes a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. The encoded protein may play a role in synapse organization and neuronal signalling. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
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UniProt Comments for Dlgap4

Function: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane

By similarity.

Subunit structure: Interacts with DLG1 and DLG4/PSD-95

By similarity.

Subcellular location: Membrane; Peripheral membrane protein

By similarity.

Sequence similarities: Belongs to the SAPAP family.

Sequence caution: The sequence BAC65690.2 differs from that shown. Reason: Intron retention.
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Research Articles on Dlgap4

1. Detection of significantly increased postsynaptic density-95 induced by behavioral training at the protein level per se is intriguing and supports the proposed importance of this molecule for neuronal information storage.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-Dlgap4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with Dlgap4 and Brain
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