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PTTG1IP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649309

The encoded protein, which directly binds to pituitary tumor-transforming protein-1 (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes… More details

$935 / 0.05 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PTTG1IP, Polyclonal Antibody
Full Product Name
PTTG1IP, ID (Pituitary Tumor-transforming Gene 1 Protein-interacting Protein, Pituitary Tumor-transforming Gene Protein-binding Factor, PBF, PTTG-binding Factor, C21orf1, C21orf3)
Product Gene Name
Product Synonym Names
Anti -PTTG1IP, ID (Pituitary Tumor-transforming Gene 1 Protein-interacting Protein, Pituitary Tumor-transforming Gene Protein-binding Factor, PBF, PTTG-binding Factor, C21orf1, C21orf3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human PTTG1IP. Species sequence homology: mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
20,324 Da
Chromosome Location
Chromosome: 21; NC_000021.8 (46269500..46294487, complement). Location: 21q22.3
OMIM
603784
3D Structure
ModBase 3D Structure for P53801
Immunogen
Synthetic peptide corresponding to human PTTG.
Applications Tested/Suitable for anti-PTTG1IP antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PTTG1IP antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:10,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-PTTG1IP antibody

Human Prostate, Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-PTTG1IP Polyclonal Antibody – Cat# MBS649309

Western Blot (WB) of anti-PTTG1IP antibody

Western blot analysis of extracts from RAW264.7 cells. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-PTTG1IP Polyclonal Antibody, Western Blot (WB) – Cat# MBS649309

Other Notes

Small volumes of anti-PTTG1IP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTTG1IP purchase

MBS649309 is an antibody targeting PTTG1IP. Also known as PTTG1IP, ID (Pituitary Tumor-transforming Gene 1 Protein-interacting Protein, Pituitary Tumor-transforming Gene Protein-binding Factor, PBF, PTTG-binding Factor, C21orf1, C21orf3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PTTG1IP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pituitary tumor-transforming gene 1 protein-interacting protein
NCBI Official Synonym Full Names
pituitary tumor-transforming 1 interacting protein
NCBI Official Symbol
PTTG1IP
NCBI Official Synonym Symbols
PBF; C21orf1; C21orf3
UniProt Protein Name
Pituitary tumor-transforming gene 1 protein-interacting protein
UniProt Synonym Protein Names
Pituitary tumor-transforming gene protein-binding factor
UniProt Gene Name
PTTG1IP
UniProt Synonym Gene Names
C21orf1; C21orf3; PBF
UniProt Entry Name
PTTG_HUMAN
NCBI Protein Information
pituitary tumor-transforming gene 1 protein-interacting protein; PTTG-binding factor; pituitary tumor-transforming gene protein-binding factor

NCBI Summary for PTTG1IP

The encoded protein, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1. [provided by RefSeq, Jul 2008]
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UniProt Comments for PTTG1IP

Function: May facilitate PTTG1 nuclear translocation.

Subunit structure: Interacts with PTTG1. Ref.2

Subcellular location: Membrane; Single-pass type I membrane protein

Potential. Cytoplasm. Nucleus. Note: According to Ref.2, it is found in the cytoplasm and the nucleus. Ref.2

Tissue specificity: Ubiquitous.

Induction: By transcription factor RUNX2. Ref.7

Sequence similarities: Contains 1 PSI domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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