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B-Cell CLL/Lymphoma 2 Like (Bcl2L) ELISA Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS065384

MBS065384 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the B-Cell CLL/Lymphoma 2 Like Protein (Bcl2L) ELISA Kit target analytes in biological samples. The concentration gradients of the… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
B-Cell CLL/Lymphoma 2 Like Protein (Bcl2L), ELISA Kit
Full Product Name
Rat B-Cell CLL/Lymphoma 2 Like Protein ELISA Kit
Product Gene Name
Bcl2L elisa kit
Species Reactivity
Rat
Preparation and Storage
Store all reagents at 2-8 degree C
Molecular Weight
157,129 Da
OMIM
609004
3D Structure
ModBase 3D Structure for Q86UU0

Other Notes

Small volumes of Bcl2L elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Bcl2L. It may not necessarily be applicable to this product.

NCBI GI #
32698936
NCBI GeneID
283149
NCBI Accession #
NP_872363.1
UniProt Primary Accession #
Q86UU0
UniProt Secondary Accession #
Q67FY1; Q6ZWJ0; Q6ZWK2; A1A4C1
UniProt Related Accession #
Q86UU0
GenBank Nucleotide #
NM_182557.2
NCBI Official Full Name
B-cell CLL/lymphoma 9-like protein
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 9-like
NCBI Official Symbol
BCL9L
NCBI Official Synonym Symbols
BCL9-2; DLNB11
UniProt Protein Name
B-cell CLL/lymphoma 9-like protein
UniProt Synonym Protein Names
Protein BCL9-2
UniProt Gene Name
BCL9L
UniProt Synonym Gene Names
DLNB11; B-cell lymphoma 9-like protein
UniProt Entry Name
BCL9L_HUMAN
NCBI Protein Information
B-cell CLL/lymphoma 9-like protein; protein BCL9-2; BCL9-like protein; B-cell lymphoma 9-like protein; nuclear co-factor of beta-catenin signalling

UniProt Comments for Bcl2L

Bcl-9L: a novel beta-catenin-interacting protein that translocates beta-catenin to the nucleus, enhancing beta-catenin mediated transcription. Can play an important role in colorectal carcinogenesis. Nuclear expression of Bcl-9L is closely associated with the high nuclear grade cancer phenotype and the expression of ErbB2/HER-2 in breast cancers.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: transcription coactivator activity; beta-catenin binding

Biological Process: transcription, DNA-dependent; somatic stem cell maintenance; regulation of cell morphogenesis; positive regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway through beta-catenin; negative regulation of transforming growth factor beta receptor signaling pathway
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Research Articles on Bcl2L

1. Data show that beta-catenin/BCL9-Like (BCL9L)/T-cell factor 4 (TCF4) signalling directly targets the GCM1/syncytin pathway and thereby regulates the fusion of human choriocarcinoma cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Bcl2L elisa kit

 Reference Product  PubMed Publications
 CTNNB1 elisa kit  >18 publications with Bcl2L and CTNNB1
 FGF20 elisa kit  >5 publications with Bcl2L and FGF20
 PHLDB1 elisa kit  >4 publications with Bcl2L and PHLDB1
 PYGO2 elisa kit  >4 publications with Bcl2L and PYGO2
 RNF26 elisa kit  >3 publications with Bcl2L and RNF26
 FOXR1 elisa kit  >2 publications with Bcl2L and FOXR1
 C2CD2L elisa kit  >1 publications with Bcl2L and C2CD2L

Pathways associated with Bcl2L elisa kit

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway antibodies  RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By WNT In Cancer Pathway antibodies  Signaling By WNT In Cancer Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 TCF Dependent Signaling In Response To WNT Pathway antibodies  TCF Dependent Signaling In Response To WNT Pathway Diagram
 XAV939 Inhibits Tankyrase, Stabilizing AXIN Pathway antibodies  XAV939 Inhibits Tankyrase, Stabilizing AXIN Pathway Diagram
 Deactivation Of The Beta-catenin Transactivating Complex Pathway antibodies  Deactivation Of The Beta-catenin Transactivating Complex Pathway Diagram
 Formation Of The Beta-catenin:TCF Transactivating Complex Pathway antibodies  Formation Of The Beta-catenin:TCF Transactivating Complex Pathway Diagram
 Misspliced LRP5 Mutants Have Enhanced Beta-catenin-dependent Signaling Pathway antibodies  Misspliced LRP5 Mutants Have Enhanced Beta-catenin-dependent Signaling Pathway Diagram

Diseases associated with Bcl2L elisa kit

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >3 publications with Bcl2L and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >1 publications with Bcl2L and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >1 publications with Bcl2L and Disease Models, Animal
 Necrosis Antibodies  >1 publications with Bcl2L and Necrosis

Organs/Tissues associated with Bcl2L elisa kit

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >2 publications with Bcl2L and Bone
 Embryonic Tissue Antibodies  >2 publications with Bcl2L and Embryonic Tissue
 Brain Antibodies  >2 publications with Bcl2L and Brain
 Eye Antibodies  >1 publications with Bcl2L and Eye
 Intestine Antibodies  >1 publications with Bcl2L and Intestine
 Prostate Antibodies  >1 publications with Bcl2L and Prostate
 Nerve Antibodies  >1 publications with Bcl2L and Nerve
 Placenta Antibodies  >1 publications with Bcl2L and Placenta
 Lung Antibodies  >1 publications with Bcl2L and Lung
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