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PD-1 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668434

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. In mice, expression of this gene is… More details

$210 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PD-1, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to mPD-1 (Clone: ABM5F42)
Product Gene Name
Product Synonym Names
Programmed cell death protein 1; Protein PD-1; CD279
Clonality
Monoclonal
Isotype
IgG2b kappa
Clone Number
ABM5F42
Host
Rat
Species Reactivity
Mouse
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein G Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
Molecular Weight
31,842 Da
3D Structure
ModBase 3D Structure for Q02242
Immunogen Information
partial length recombinant protein (a.a 07-211) of mPD-1 was used as the immunogen for this antibody.
Antigen
mPD-1
Conjugate
Unconjugated

Product Categories/Family for anti-PD-1 antibody

Applications Tested/Suitable for anti-PD-1 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-PD-1 antibody
Flow Cytometry: 0.5-1 ug/10^6

Flow Cytometry (FC/FACS) of anti-PD-1 antibody

Fig: 1- Cell surface flow analysis of mPD-1 in Con A treated Mouse Splenocytes using 0.5 ug/10^6 cells of mPD-1 antibody (Clone: ABM5F42). Green represents isotype control; red represents anti-mPD-1 antibody. Goat anti-rat PE conjugate was used as secondary antibody.
Rat Anti-PD-1 Monoclonal Antibody – Cat# MBS668434

Other Notes

Small volumes of anti-PD-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PD-1 purchase

MBS668434 is an antibody targeting PD-1. Also known as Monoclonal Antibody to mPD-1 (Clone: ABM5F42). Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for PD-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Programmed cell death protein 1
NCBI Official Synonym Full Names
programmed cell death 1
NCBI Official Symbol
Pdcd1
NCBI Official Synonym Symbols
PD-1; Pdc1; Ly101
UniProt Protein Name
Programmed cell death protein 1
UniProt Synonym Protein Names
CD_antigen: CD279
UniProt Gene Name
Pdcd1
UniProt Synonym Gene Names
Pd1; Protein PD-1; mPD-1
NCBI Protein Information
programmed cell death protein 1

UniProt Comments for PD-1

PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse 'exhausted' T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1|1 D

Cellular Component: external side of plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: negative regulation of apoptosis; negative regulation of tolerance induction; positive regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-PD-1 antibody

 Organ/Tissue Name  Pubmed Publications
 Thymus Antibodies  >22 publications with PD-1 and Thymus
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