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KLF10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668698

Kruppel-like factor 10 (KLF10) is a member of the Kruppel-like family of transcription factors, which are known to be involved in anti-proliferative and apoptotic inducing functions following TGF-beta induction. KLF10 plays an important role in the repression… More details

$200 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLF10, Polyclonal Antibody
Full Product Name
Polyclonal Antibody to KLF10
Product Gene Name
anti-KLF10 antibody
Product Synonym Names
KLF10; TIEG; TIEG1; EGR-alpha; TGFB-inducible early growth response protein 1; Transforming growth factor-beta-inducible early growth response protein 1; Antibody to KLF10; Anti-KLF10 Antibody; KLF10 Antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Predicted: Mouse
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein A Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
Molecular Weight
13,702 Da
OMIM
S81439 mRNA
3D Structure
ModBase 3D Structure for Q13118
Immunogen Information
A partial length recombinant KLF10 protein (amino acids 11-221) was used as the immunogen for this antibody.
Antigen
KLF10

Product Categories/Family for anti-KLF10 antibody

Antibodies; Cell Signalling
Applications Tested/Suitable for anti-KLF10 antibody
Western Blot (WB)
Application Notes for anti-KLF10 antibody
WB: 1-2 ug/ml

Western Blot (WB) of anti-KLF10 antibody

Fig-1: Western blot analysis of KLF10. Anti-KLF10 antibody (11-8067) was used at 1 ug/ml on Hela lysate.
Rabbit Anti-KLF10 Polyclonal Antibody – Cat# MBS668698

Other Notes

Small volumes of anti-KLF10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLF10 purchase

MBS668698 is an antibody targeting KLF10. Also known as Polyclonal Antibody to KLF10. Reactive in Human
Predicted: Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLF10. It may not necessarily be applicable to this product.

NCBI GI #
11387050
NCBI GeneID
7071
NCBI Accession #
Q13118.1
UniProt Primary Accession #
Q13118
UniProt Secondary Accession #
O75411; Q503B2; A8MVH0; B2R794; L0R4P6; L0R679
UniProt Related Accession #
Q13118
NCBI Official Full Name
Krueppel-like factor 10
NCBI Official Synonym Full Names
Kruppel like factor 10
NCBI Official Symbol
KLF10
NCBI Official Synonym Symbols
EGRA; TIEG; TIEG1; EGR-alpha
UniProt Protein Name
Krueppel-like factor 10
UniProt Synonym Protein Names
EGR-alpha; Transforming growth factor-beta-inducible early growth response protein 1; TGFB-inducible early growth response protein 1; TIEG-1
Protein Family
Krueppel-like factor
UniProt Gene Name
KLF10
UniProt Synonym Gene Names
TIEG; TIEG1; TGFB-inducible early growth response protein 1; TIEG-1
NCBI Protein Information
Krueppel-like factor 10

NCBI Summary for KLF10

This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
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UniProt Comments for KLF10

KLF10: Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'. Belongs to the Sp1 C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 8q22.3

Cellular Component: nucleus

Molecular Function: protein binding; transcription factor activity

Biological Process: cell proliferation; cell-cell signaling; cellular response to starvation; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of circadian rhythm; skeletal development; transforming growth factor beta receptor signaling pathway
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Research Articles on KLF10

1. photoexposure decreases expression in fibroblasts and keratinocytes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KLF10 antibody

 Reference Product  PubMed Publications
 SP1 antibody  >18 publications with KLF10 and SP1
 TGFB1 antibody  >11 publications with KLF10 and TGFB1
 SMAD7 antibody  >9 publications with KLF10 and SMAD7
 FOXP3 antibody  >6 publications with KLF10 and FOXP3
 BMP2 antibody  >4 publications with KLF10 and BMP2
 MYCN antibody  >1 publications with KLF10 and MYCN
 FLT1 antibody  >1 publications with KLF10 and FLT1

Diseases associated with anti-KLF10 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >14 publications with KLF10 and Carcinoma
 Inflammation Antibodies  >12 publications with KLF10 and Inflammation
 Cardiovascular Diseases Antibodies  >10 publications with KLF10 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >7 publications with KLF10 and Disease Models, Animal
 Breast Neoplasms Antibodies  >6 publications with KLF10 and Breast Neoplasms
 Adenocarcinoma Antibodies  >6 publications with KLF10 and Adenocarcinoma
 Pancreatic Neoplasms Antibodies  >6 publications with KLF10 and Pancreatic Neoplasms
 Fibrosis Antibodies  >4 publications with KLF10 and Fibrosis
 Liver Diseases Antibodies  >4 publications with KLF10 and Liver Diseases
 Hypertrophy Antibodies  >3 publications with KLF10 and Hypertrophy

Organs/Tissues associated with anti-KLF10 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >23 publications with KLF10 and Bone
 Blood Antibodies  >17 publications with KLF10 and Blood
 Liver Antibodies  >9 publications with KLF10 and Liver
 Muscle Antibodies  >8 publications with KLF10 and Muscle
 Vascular Antibodies  >8 publications with KLF10 and Vascular
 Connective Tissue Antibodies  >7 publications with KLF10 and Connective Tissue
 Brain Antibodies  >7 publications with KLF10 and Brain
 Pancreas Antibodies  >6 publications with KLF10 and Pancreas
 Bone Marrow Antibodies  >5 publications with KLF10 and Bone Marrow
 Kidney Antibodies  >5 publications with KLF10 and Kidney
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