• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

mTLR9 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668969

Mouse Toll-like receptor 9 (mTLR9) is an innate immune sensor for microbial DNA that erroneously responds to self DNA in autoimmune disease. TLR9 is normally expressed in endosomes/lysosomes where it is activated by pathogen-derived DNA. It has modulatory… More details

$385 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
mTLR9, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to mTLR9 (Clone: ABM4D70) FITC Conjugated
Product Gene Name
Product Synonym Gene Name
Tlr9
Product Synonym Names
Tlr9; CD289
Clonality
Monoclonal
Isotype
IgG2a Kappa
Clone Number
ABM4D70
Host
Rat
Species Reactivity
Mouse
Form/Format
0.2 mg/ml in Tris buffer containing 0.05% Azide
Purity/Purification
Purified
Protein G Chromatography
Preparation and Storage
Store the antibody at 4 degree C; stable for 6 months.
Molecular Weight
116,412 Da
3D Structure
ModBase 3D Structure for Q9EQU3
Antigen
mTLR9
Immunogen Information
A partial length recombinant mTLR9 protein (amino acids 602-860) was used as the immunogen for this antibody.
Conjugation
FITC

Product Categories/Family for anti-mTLR9 antibody

Applications Tested/Suitable for anti-mTLR9 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-mTLR9 antibody
FC/FACS: 0.25-1 ug/10^6 cells

Flow Cytometry (FC/FACS) of anti-mTLR9 antibody

Fig-1: Intracellular flow analysis of FITC-conjugated mTLR9 antibody in mouse splenocytes using 0.25 ug/10^6 cells of FITC-conjugated mTLR9 antibody (Clone: ABM4D70). Green represents isotype control; red represents anti-mTLR9 antibody conjugated with FITC.
Rat Anti-mTLR9 Monoclonal Antibody – Cat# MBS668969

Other Notes

Small volumes of anti-mTLR9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mTLR9 purchase

MBS668969 is an antibody targeting mTLR9. Also known as Monoclonal Antibody to mTLR9 (Clone: ABM4D70) FITC Conjugated. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for mTLR9. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
toll-like receptor 9
NCBI Official Synonym Full Names
toll-like receptor 9
NCBI Official Symbol
Tlr9
UniProt Protein Name
Toll-like receptor 9
UniProt Synonym Protein Names
CD_antigen: CD289
UniProt Gene Name
Tlr9
NCBI Protein Information
toll-like receptor 9

UniProt Comments for mTLR9

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:18931679, PubMed:21402738, PubMed:14993594, PubMed:17474149, PubMed:25686612, PubMed:18820679). Plays a role in defense against systemic mouse cytomegalovirus infection (PubMed:14993594). Controls lymphocyte response to Helicobacter infection (PubMed:17474149). Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production ().
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000