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KEX-2 Yeast Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691718

Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Kex-2, Active Protein
Full Product Name
Yeast Kex-2
Product Gene Name
Product Synonym Names
Endoproteinase Lys/Arg-Arg; Protease KEX2; Proteinase YSCF
Sequence
LPVPAPPMDS SLLPVKEAED KLSINDPLFE RQWHLVNPSF PGSDIN VLDL WYNNITGAGV VAAIVDDGLD YENEDLKDNF CAEGSWDFND N TNLPKPRLS DDYHGTRCAG EIAAKKGNNF CGVGVGYNAK ISGIRIL SGD ITTEDEAASL IYGLDVNDIY SCSWGPADDG RHLQGPSDLV KK ALVKGVTE GRDSKGAIYV FASGNGGTRG DNCNYDGYTN SIYSITIG AI DHKDLHPPYS EGCSAVMAVT YSSGSGEYIH SSDINGRCSN SHG GTSAAAP LAAGVYTLLL EANPNLTWRD VQYLSILSAV GLEKNADGD W RDSAMGKKYS HRYGFGKIDA HKLIEMSKTW ENVNAQTWFY LPTL YVSQST NSTEETLESV ITISEKSLQD ANFKRIEHVT VTVDIDTEIR GTTTVDLISP AGIISNLGVV RPRDVSSEGF KDWTFMSVAH WGENG VGDWK IKVKTTENGH RIDFHSWRLK LFGESIDSSK TETFVFGNDK EEVEPAATES TVSQYSASST SISISATSTS SISIGVETSA IPQTTT ASTD PDSDPNTP
Host
Insect Cells
Species Reactivity
Yeast
Form/Format
Lyophilized
Purity/Purification
> 95% by SDS-PAGE & HPLC analyses
Molecular Weight
90,003 Da
Chromosome Location
Chromosome: XIV; NC_001146.8 (202428..204872). Location: chromosome: XIV
3D Structure
ModBase 3D Structure for P13134
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Recombinant Kex-2 from High-5 insect cells contains the same specific activity and recognition sequence specificity as yeast derived KEX-2. 1 milligram of recombinant KEX-2 contains activity equivalent to at least 40 units of yeast derived KEX-2. Cleaves at the carboxyl side of K/R-R.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of Kex-2 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Kex-2 purchase

MBS691718 is an active protein targeting Kex-2. Also known as Yeast Kex-2. Reactive in Yeast. Host: Insect Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for Kex-2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Kex2p
NCBI Official Symbol
KEX2
NCBI Official Synonym Symbols
QDS1; SRB1; VMA45
UniProt Protein Name
Kexin
UniProt Synonym Protein Names
Protease KEX2; Proteinase YSCF
UniProt Gene Name
KEX2
UniProt Synonym Gene Names
QDS1
UniProt Entry Name
KEX2_YEAST
NCBI Protein Information
Kex2p

UniProt Comments for Kex-2

Function: Processing of precursors of alpha-factors and killer toxin.

Catalytic activity: Cleavage of -Lys-Arg-|-Xaa- and -Arg-Arg-|-Xaa- bonds to process yeast alpha-factor pheromone and killer toxin precursors.

Cofactor: Binds 3 calcium ions per subunit.

Subcellular location: Golgi apparatus › trans-Golgi network membrane; Single-pass type I membrane protein.

Post-translational modification: O-glycosylated.

Sequence similarities: Belongs to the peptidase S8 family. Furin subfamily.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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