• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IL-19 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS695136

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIL-19. Anti-Human IL-19 specific antibody was purified by affinity chromatography and then biotinylated. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
IL-19, Polyclonal Antibody
Full Product Name
Biotinylated Anti-hIL-19
Product Gene Name
anti-IL-19 antibody
Product Synonym Names
Biotinylated Anti-Human IL-19
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Biotin
Preparation and Storage
At -20 degree C
Molecular Weight
23,079 Da
OMIM
605687
3D Structure
ModBase 3D Structure for Q9UHD0
Immunogen
Recombinant Human IL-19
Applications Tested/Suitable for anti-IL-19 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-IL-19 antibody
Direct Detection: To detect hIL-19 by direct ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIL-19.

Sandwich ELISA: To detect hIL-19 by sandwich ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with Polyclonal Anti-Human IL-19 as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIL-19.

Western Blot: To detect hIL-19 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-19 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-IL-19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-19 purchase

MBS695136 is an antibody targeting IL-19. Also known as Biotinylated Anti-hIL-19. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-19. It may not necessarily be applicable to this product.

NCBI GI #
146345440
NCBI GeneID
29949
NCBI Accession #
Q9UHD0.2
UniProt Primary Accession #
Q9UHD0
UniProt Secondary Accession #
Q5VUT3; Q96QR4; Q9NUA0; B6VEV9
UniProt Related Accession #
Q9UHD0
NCBI Official Full Name
Interleukin-19
NCBI Official Synonym Full Names
interleukin 19
NCBI Official Symbol
IL19
NCBI Official Synonym Symbols
MDA1; NG.1; ZMDA1; IL-10C
UniProt Protein Name
Interleukin-19
UniProt Synonym Protein Names
Melanoma differentiation-associated protein-like protein; NG.1
UniProt Gene Name
IL19
UniProt Synonym Gene Names
ZMDA1; IL-19
UniProt Entry Name
IL19_HUMAN
NCBI Protein Information
interleukin-19; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein

NCBI Summary for IL-19

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for IL-19

IL19: May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. Belongs to the IL-10 family.

Protein type: Cytokine; Secreted, signal peptide; Apoptosis; Secreted

Chromosomal Location of Human Ortholog: 1q32.2

Cellular Component: extracellular space; extracellular region

Molecular Function: cytokine activity

Biological Process: apoptosis; positive regulation of JAK-STAT cascade; immune response; inflammatory response; signal transduction; interleukin-6 biosynthetic process
Show more

Research Articles on IL-19

1. It supresses inflammation and its gene deletion causes inflammatory bowel disease.(review)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL-19 antibody

 Reference Product  PubMed Publications
 IL13 antibody  >4 publications with IL-19 and IL13
 IL20RA antibody  >3 publications with IL-19 and IL20RA
 SOCS5 antibody  >1 publications with IL-19 and SOCS5
 IL23R antibody  >1 publications with IL-19 and IL23R
 IL23A antibody  >1 publications with IL-19 and IL23A

Pathways associated with anti-IL-19 antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL23-mediated Signaling Events Pathway antibodies  IL23-mediated Signaling Events Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram

Diseases associated with anti-IL-19 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >29 publications with IL-19 and Inflammation
 Skin Diseases Antibodies  >22 publications with IL-19 and Skin Diseases
 Disease Models, Animal Antibodies  >10 publications with IL-19 and Disease Models, Animal
 Asthma Antibodies  >9 publications with IL-19 and Asthma
 Carcinoma Antibodies  >6 publications with IL-19 and Carcinoma
 Colitis Antibodies  >5 publications with IL-19 and Colitis
 Kidney Diseases Antibodies  >4 publications with IL-19 and Kidney Diseases
 Respiratory Hypersensitivity Antibodies  >4 publications with IL-19 and Respiratory Hypersensitivity
 Hypersensitivity Antibodies  >4 publications with IL-19 and Hypersensitivity
 Atherosclerosis Antibodies  >4 publications with IL-19 and Atherosclerosis

Organs/Tissues associated with anti-IL-19 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >10 publications with IL-19 and Lung
 Mixed Antibodies  >1 publications with IL-19 and Mixed
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000