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Exodus-2 (CCL21) Mouse Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS696182

Exodus-2 is a CC chemokine that can signal through the CCR7 receptor. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Exodus-2 (CCL21), Active Protein
Full Product Name
Murine Exodus-2 (CCL21)
Product Gene Name
Product Synonym Names
Recombinant Murine Exodus-2 (CCL21)
Sequence
SDGGGQDCC LKYSQKKIP YSIVRGYRK QEPSLGCPI PAILFLPRK HSKPELCAN PEEGWVQNL MRRLDQPPA PGKQSPGCR KNRGTSKSG KKGKGSKGC KRTEQTQPS RG
Host
E Coli
Species Reactivity
Species Reactivity: Mouse
Cross Reactivity: Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Preparation and Storage
At -20 degree C
Molecular Weight
14,584 Da
3D Structure
ModBase 3D Structure for P86792
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Determined by its ability to chemoattract total murine T cell population using a concentration range of 10.0-100.0 ng/ml.
Cell Type
B Cells, T Cells, Endothelial Cells

Testing Data of CCL21 active protein

Mouse CCL21 Active Protein – Cat# MBS696182

Other Notes

Small volumes of CCL21 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL21 purchase

MBS696182 is an active protein targeting CCL21. Also known as Murine Exodus-2 (CCL21). Reactive in Species Reactivity: Mouse
Cross Reactivity: Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL21. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
C-C motif chemokine 21b
NCBI Official Synonym Full Names
predicted gene 10591
NCBI Official Symbol
Gm10591
NCBI Official Synonym Symbols
ENSMUSG00000073869
UniProt Protein Name
C-C motif chemokine 21b
UniProt Synonym Protein Names
6Ckine; Beta-chemokine exodus-2; Small-inducible cytokine A21b; Thymus-derived chemotactic agent 4; TCA4
Protein Family
UniProt Gene Name
Ccl21b
UniProt Synonym Gene Names
Scya21; Scya21b; TCA4
UniProt Entry Name
CC21B_MOUSE
NCBI Protein Information
predicted gene 10591

UniProt Comments for CCL21

CCL21b: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T- cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Chemokine; Motility/polarity/chemotaxis

Cellular Component: external side of plasma membrane

Molecular Function: chemokine receptor binding; chemokine activity

Biological Process: negative regulation of myeloid cell differentiation; leukocyte chemotaxis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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