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Integrator Complex Subunit 3 (INTS3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS710662

MBS710662 is an antibody targeting INTS3. Also known as Rabbit anti-human integrator complex subunit 3 polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
integrator complex subunit 3 (INTS3), Polyclonal Antibody
Full Product Name
Rabbit anti-human integrator complex subunit 3 polyclonal Antibody
Product Gene Name
Product Synonym Names
integrator complex subunit 3; INTS3; C1orf193; C1orf60; DKFZp686E1950; DKFZp686O20115; DKFZp781I1253; FLJ21919; FLJ44849; INT3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
63,586 Da
OMIM
611347
Immunogen
Human INTS3
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-138355
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-INTS3 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-INTS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for INTS3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrator complex subunit 3
NCBI Official Synonym Full Names
integrator complex subunit 3
NCBI Official Symbol
INTS3
NCBI Official Synonym Symbols
INT3; SOSSA; SOSS-A; C1orf60; C1orf193
UniProt Protein Name
Integrator complex subunit 3
UniProt Synonym Protein Names
SOSS complex subunit A; Sensor of single-strand DNA complex subunit A; SOSS-A; Sensor of ssDNA subunit A
Protein Family
UniProt Gene Name
INTS3
UniProt Synonym Gene Names
C1orf193; C1orf60; Int3; SOSS-A; Sensor of ssDNA subunit A
UniProt Entry Name
INT3_HUMAN
NCBI Protein Information
integrator complex subunit 3; sensor of ssDNA A; SOSS complex subunit A; sensor of ssDNA subunit A; sensor of single-strand DNA complex subunit A

NCBI Summary for INTS3

INTS3 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]). INTS3 is also a subunit of single-stranded DNA (ssDNA)-binding complexes involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]
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UniProt Comments for INTS3

INTS3: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Belongs to the Integrator subunit 3 family. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleus; integrator complex

Molecular Function: protein binding

Biological Process: mitotic cell cycle checkpoint; snRNA processing; response to ionizing radiation; DNA repair; response to DNA damage stimulus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-INTS3 antibody

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