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Core-Binding Factor, Runt Domain, Alpha Subunit 2; Translocated to, 3 (CBFA2T3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS711646

MBS711646 is an antibody targeting CBFA2T3. Also known as Rabbit anti-human core-binding factor, runt domain, alpha subunit 2; translocated to, 3 polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (CBFA2T3), Polyclonal Antibody
Full Product Name
Rabbit anti-human core-binding factor, runt domain, alpha subunit 2; translocated to, 3 polyclonal Antibody
Product Gene Name
Product Synonym Names
core-binding factor; runt domain; alpha subunit 2; translocated to; 3; CBFA2T3; ETO2; MTG16; MTGR2; ZMYND4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
7,436 Da
OMIM
603870
Immunogen
Human CBFA2T3
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9741 / sc-9739 / sc-9738 / sc-28694
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CBFA2T3 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-CBFA2T3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CBFA2T3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Core-binding factor, runt domain, alpha subunit 2; translocated to, 3
NCBI Official Synonym Full Names
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
NCBI Official Symbol
CBFA2T3
NCBI Official Synonym Symbols
ETO2; MTG16; MTGR2; ZMYND4
UniProt Protein Name
Protein CBFA2T3
UniProt Synonym Protein Names
MTG8-related protein 2; Myeloid translocation gene on chromosome 16 protein; hMTG16; Zinc finger MYND domain-containing protein 4
Protein Family
UniProt Gene Name
CBFA2T3
UniProt Synonym Gene Names
MTG16; MTGR2; ZMYND4; hMTG16
UniProt Entry Name
MTG16_HUMAN
NCBI Protein Information
protein CBFA2T3; MTG8-related gene 2; MTG8-related protein 2; myeloid translocation gene 8 and 16b; zinc finger MYND domain-containing protein 4; myeloid translocation gene on chromosome 16 protein

NCBI Summary for CBFA2T3

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
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UniProt Comments for CBFA2T3

CBFA2T3: a transcriptional repressor encoded by a gene on chromosome arm 16q, the second most frequent target of loss of heterozygosity in breast cancer. May have tumour suppressor activity. Interacts with ZNF652, a novel zinc finger protein, to repress transcription.

Protein type: Nucleolus; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: Golgi membrane; nucleoplasm; nucleolus; nucleus

Molecular Function: protein binding; metal ion binding; chromatin binding; transcription corepressor activity; transcription factor activity

Biological Process: cell proliferation; transcription, DNA-dependent; granulocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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